Relationship Of Nonalcoholic Fatty Liver Disease With Body Fat

Objective:In order to investigate the relationship of nonalcohol fatty liver disease with body fat and related risk factors.Methods:A total of 611 subjects with complete information were included by collecting people who came to the First Affiliated Hospital of Guangxi Medical University for health examination from March 2011 to September 2013.All subjects were included of 380 males and 231 females. Fatty liver were tested by ultrasound doctors and made a report. The total body fat percentage was measured by using dual-energy x-ray analyzer (DEXA). Detail informations were recorded including age, gender, height, weight,systolic blood pressure(SBP), diastolic blood pressure (DBP), body mass index (BMI),previous history. Measurement of total cholesterol (TC),triglyceride (TG),high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C),alanine aminotransferase (ALT), aspartate aminotransferase (AST),fasting blood glucose(FPG),Uric acid(UA).In order to investigate the relationship of nonalcohol fatty liver disease with total body fat percentage and related risk factors.Results:1.The total body fat percentage of NAFLD group was higher than the control group (P<0.05).2.Compared with the control group,NAFLD group had higher BMI, SBP, DBP, TC, TG, LDL-C, ALT, AST, FPG,UA, but lower HDL-C,and the difference is statistically significant (P< 0.05).3.With the increase of total body fat percentage, BMI, SBP, TC, TG, LDL-C were increasing,and the difference is statistically significant (P<0.05).4.NAFLD have close relation with the total body fat percentage.5.The areas under the ROC curve of male and female of the total body fat percentage are 0.906,0.825, suggest that the total percentage of body fat has a predictive of NAFLD.Conclusion:1.The total body fat percentage of nonalcoholic fatty liver disease patients was higher than the control group.2.The total body fat percentage have close relation with NAFLD,the total body fat percentage was risk factor for NAFLD.3.The total body fat percentage can be used to predict the risk of NAFLD, and men has a higher predict value than women.