The Study Of Hemodynamics Of Vertebral-basilar Artery And Ophthalmic Artery In Patients With Sudden Deafness

Objective: Sudden deafness refers to unexplained sudden hearing loss of one or both ears, In recent years, studies have found the prevalence of sudden deafness has increased dramatically, while the cause of sudden deafness is not yet clear. At present, sudden deafness is diagnosed mainly by hearing loss type, degree, onset time, duration of disease. The cause mechanism of sudden deafness has been controversial, and there has been no reasonable and detailed planning about the treatment. To find a common pathophysiological mechanism in the development process of the disease has important clinical significance for the treatment of sudden deafness.Scholars generally support Microcirculation Disturbances as the cause of sudden deafness. Sudden deafness is divided into the following three categories: sudden deafness with low-frequency hearing loss curve; sudden deafness with high-frequency hearing loss curve; sudden deafness with all-frequency hearing loss curve. This study aims to observe the hemodynamics of vertebral-basilar artery and ophthalmic artery of patients with the mentioned sudden deafness and healthy persons through the use of Color-Doppler, and to explore whether there are Microcirculation Disturbances in patients with sudden deafness, thereby providing a valuable theoretical basis for clinical prevention and treatment of sudden deafness.Methods: 20 cases of healthy persons, 56 cases of patients with sudden deafness, referring to the Germany classification frequency hearing loss curve[6], The case group is divided into three groups: 21 cases of sudden deafness patients with low-frequency hearing loss curve, 16 cases of sudden deafness patients with high-frequency hearing loss curve, 19 cases of sudden deafness patients with all-frequency hearing loss curve. Subjects were treated with clinically and unified treatment for 10 days.The hearing table of the case group and control group are measured by the Madsen Conera 1 ~ 3 audiometer. Measure the hemodynamics of vertebral-basilar artery of patients with the mentioned sudden deafness and healthy persons through the use of Color-Doppler PHILIPS-IE33; and Measure the hemodynamics of ophthalmic artery of patients with the mentioned sudden deafness and healthy persons through the use of Color-Doppler PHILIPS-IU22. The goal of treatment was to observe whether there are differences in the hemodynamics of vertebral-basilar artery and ophthalmic artery between patients with the mentioned sudden deafness and healthy persons.Results: 1 The hemodynamics of vertebral-basilar artery and ophthalmic artery of sudden deafness patients with different frequency hearing loss curve before treatment. 1.1 The hemodynamics of vertebral-basilar artery of sudden deafness patients with different frequency hearing loss curve before treatment.Peak systolic velocity and pulsatility index of Vertebral artery and basilar artery are not statistically significant between sudden deafness patients with low-frequency hearing loss curve and healthy persons(P<0.05).Peak systolic velocity of Vertebral artery and basilar artery is reduced, and which is statistically significant between sudden deafness patients with high-frequency hearing loss curve and healthy persons(P<0.05). But, pulsatility index of Vertebral artery and basilar artery are not statistically significant(P>0.05).Peak systolic velocity of Vertebral artery and basilar artery is increased, and which is statistically significant between sudden deafness patients with all-frequency hearing loss curve and healthy persons( P < 0.05). But, pulsatility index of Vertebral artery and basilar artery are not statistically significant(P>0.05). 1.2 The hemodynamics of ophthalmic artery of sudden deafness patients before treatment.Peak systolic velocity and resistance index of the contralateral eye’s ophthalmic artery are not statistically significant between sudden deafness patients with different frequency hearing loss curve and healthy persons(P>0.05). Peak systolic velocity of the affected eye’s ophthalmic artery is reduced, and the resistance index of the affected eye’s ophthalmic artery is increased. They are both statistically significant between sudden deafness patients with different frequency hearing loss curve and healthy persons(P<0.05). 2 The hemodynamics of vertebral-basilar artery and ophthalmic artery of sudden deafness patients after treatment. 2.1 The hemodynamics of vertebral-basilar artery of sudden deafness patients with different frequency hearing loss curve after treatment.Peak systolic velocity and pulsatility index of vertebral artery and basilar artery are both not statistically significant between sudden deafness patients with low-frequency hearing loss curve and healthy persons(P>0.05). And they are both not statistically significant comparing to these before treatment(P>0.05).Peak systolic velocity and pulsatility index of vertebral artery and basilar artery are both not statistically significant between sudden deafness patients with high-frequency hearing loss curve and healthy persons(P>0.05). But they are both statistically significant comparing to these before treatment(P<0.05).Peak systolic velocity and pulsatility index of vertebral artery and basilar artery are both not statistically significant between sudden deafness patients with all-frequency hearing loss curve and healthy persons(P>0.05). But they are both statistically significant comparing to these before treatment(P<0.05). 2.2 The hemodynamics of ophthalmic artery of sudden deafness patients after treatment.Peak systolic velocity of the affected eye’s ophthalmic artery is increased, and the resistance index of the affected ophthalmic artery is reduced. They are both not statistically significant between sudden deafness patients with different frequency hearing loss curve and healthy persons(P<0.05). But they are both statistically significant comparing to these before treatment(P>0.05) 3 The total treatment efficiency comparison of each groupThe total treatment efficiency of the group of sudden deafness patients with low-frequency hearing loss curve is 95%。The total treatment efficiency of the group of sudden deafness patients with high-frequency hearing loss curve is 38%。The total treatment efficiency of the group of sudden deafness patients with all-frequency hearing loss curve is 63%。The total treatment efficiency among the three groups is statistically significant.Conclusion:1 The hemodynamics of vertebral-basilar artery and the affected eye’s ophthalmic artery of sudden deafness patients with different frequency hearing loss curve is different from healthy persons′. 2 The hemodynamics of vertebral-basilar artery and the affected eye’s ophthalmic artery of sudden deafness patients with different frequency hearing loss curve after treatment is the same with healthy persons′. 3 There is a certain relationship between the incidence of sudden deafness and Microcirculation Disturbances. 4 The total treatment efficiency of sudden deafness patients with different frequency hearing loss curve is different.