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Fufang Ejiao Jiang Analysis Of Clinical Observatioan Of Protective Effect Of Bone Marrowand Groupinfluence T Cell Subsets For Luang Cancer Patients

Posted on:2015-01-28Degree:MasterType:Thesis
Country:ChinaCandidate:L L ChengFull Text:PDF
GTID:2284330461492457Subject:Oncology
Abstract/Summary:PDF Full Text Request
Purpose:By detecting Fufang ejiao jiang group and non-Fufang ejiao jiang group diagnosed with advanced non-small cell lung cancer(NSCLC IIIA-IV stage) before and after chemotherapy routine blood(white blood cells,neutrophils, hemoglobin,platelets) and T cell subsets(CD3 +,CD4 +, CD8 +, CD4/CD8) changes and compared to observe the effect of compound a mortar for patients with advanced lung cancer chemotherapy and bone marrow function immunizations and observe Fufang ejiao jiang can help chemotherapy successfully completed。 Methods:Research collected in our hospital from January 2012 to February 2014 in patients with advanced non-cell lung cancer,stage IIIA-IV for the period, ECOG score ≤2 points in the experimental group of 20 patients in the control group,22 patients in the experimental group: combined oral chemotherapy Fufang ejiao jiang, 20ml(1 branch),,three times a day,and even served 21 days in the control group: chemotherapy,both groups completed two treatment cycles,we will be before the first cycle of chemotherapy and 3 cycles of chemotherapy before the blood conventional and T cell subsets as observed indicators, using blood analyzer WBC,neutrophil,hemoglobin,platelets, using flow cytometry of peripheral blood T cell subsets were observed in the experimental group and the control group routine blood, T cell subsets or without distinction,for statistical observation Fufang ejiao jiang whether the protective effect of bone marrow and can enhance the body’s adaptive immune function, and observe whether Fufang ejiao jiang help the successful completion of chemotherapy。 Results:After 2 cycles of chemotherapy were treated group compared with control group of white blood cells,neutrophils,hemoglobin difference was statistically significant, P <0.05,,respectively 0.016,0.004,0.030,platelet treatment group and control group,CD4 +, CD8 +, CD4 / CD8 + difference was not statistically significant, P values were 0.996,0.446,0.594,0.621。Because after chemotherapy total T CD3 + T cells P less than 0.05, heterogeneity of variance,not as observed。 Conclusion:Fufang ejiao jiang chemotherapy can increase the patient’s white blood cells,neutrophils,,hemoglobin level,platelet little effect on CD4 + T cells,CD8 + T cells,CD4/CD8 no effect, Fufang ejiao jiang not elevated platelet and enhance patient immunization function。 Meaning:Fufang ejiao jiang after chemotherapy can improve the WBC, neutrophil bone marrow suppression,anemia symptoms,had no effect on platelet function and body immunization,suggesting Fufang ejiao jiang contribute to the successful completion of chemotherapy。...
Keywords/Search Tags:Fufang ejiao jiang, Advanced non-small cell lung cancer, Routine blood T cell subsets, Hematology Analyzer, Flow Cytometry
PDF Full Text Request
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