The Security Analysis Of Portal Hypertension With Hypersplenism After Splenectomy:116 Cases Report

Objective Cirrhosis of the liver, as one of the common causes of portal hypertension, leads to liver function compensatory,that could cause portal hypertension which is the most common cause of hypersplenism. Currently, the therapy approach of portal hypertension combined the hypersplenism is mainly surgery. In this study, Patients with portal hypertension combined the hypersplenism, who had a splenectomy at First Hospital Affiliated to Lanzhou University in January 2013-December 2014 were taken as research objects to explore the relationship of splenectomy to portal hypertension combined the hypersplenism and perioperative safety and the influence of splenectomy on body. Methods Collect the data of 116 patients with portal hypertension combined the hypersplenism, who had a splenectomy at First Hospital Affiliated to Lanzhou University in January 2013-December 2014. The splenectomy was divided into the simple splenectomy, disconnection, bypass surgery and disconnectioncombinedbypass surgery based on the indications for surgery. Observe preoperative and postoperative 7 days,1 month,3 months,6months recovery and complications index. Results Among different groups,sex, smoking, alcohol consumption, hypertension, diabetes, heart disease, hepatitis B, hepatitis C, liver function A grade, B grade ratio, age, weight, height, diameter and thickness of the spleen, platelets, hemoglobin, white blood cells, urea nitrogen, creatinine, total bilirubin, aspartate aminotransferase, alanine aminotransferase, intraoperative colloid fluid volume were not significantly different (P>0.05), however on the amount of bleeding during surgery, liquid crystals, the number of blood transfusions and no, the transverse splenic flexure and tail of the pancreas damage, there are differences (P<0.05) ontotal time surgical aspects. Left pleural effusion occurs, spleen nest limitations effusion, left subphrenic effusion, wound infection, splenic fever, the rate of pancreatic fistula and spleen nest bloody drainage, albumin index were not significantly different (P>0.05), while in aspartate aminotransferaseand alanine aminotransferase indicators, there are differences (P<0.05) among different groups,7 days, one month, and 3 months after surgery; Across all outcome measures after six months there was no significant difference (P>0.05). Smoking, alcohol consumption, hypertension, diabetes, heart disease don’t have significantly influenceon increasing the risk of intraoperative and postoperative complication (P>0.05), hepatitis B, hepatitis C for increasing the probability of the risk of intraoperative and postoperative complication rates is 4.21 and 4.33 times to the normal people.Conclusion Portal hypertension merge hypersplenism purposes splenectomy is feasible and safe, and with the development of medical technology, increased security than in the past, the portal hypertension caused by gastrointestinal bleeding should be taken on the basis of different indications different surgical methods. Past hepatitis B, hepatitis C are the influence on increasing the risk of intraoperative and postoperative complicationoccurrence rate.