A Study Of The Relationship Between Pulse Wave Velocity And Diastolic Dysfunction Of Heart Failure With Preserved Ejection Fraction

Objectives To study the relationship between pulse wave velocity (PWV) and diastolic dysfunction of heart failure with preserved ejection fraction (HFpEF).Methods 40 patients with HFpEF were chosen as the study group, while 52 healthy people at the same time were chosen as the control group. Age and sex were matched. Pulse wave velocity and Transthoracic Echocardiography were tested. Laboratory examination such as NT-proBNP、FPG etc. were examed for this study. Compared with the control group in each item to find out if difference existed. The relationship between these items were analyzed.Results Compared with the control group,the study group got an high level of carotid-femoral pulse wave velocity (C-FPWV), systolic blood pressure (SBP), diastolic blood pressure (DBP),mean arterial pressure (MAP),pulse pressure (PP),uric acid (UA) and fasting plasma glucose (FPG). C-FPWV was significantly correlated with age, smoking, drinking, SBP, MAP, PP and FPG. The relationship between C-FPWV and items for diastolic dysfunction such as left ventricular mass index (LVMi-L), left atrial volume index (LAVi), left atrial diameter index (LADi), E/E’L ratio (E:peak early diastolic mitral inflow velocity; E’L:early velocity of lateral), E/E’S ratio(E’S:early velocity of septal),M E/E’ratio(average of E’L and E’S) and logNT-proBNP are significant.Conclusion The relationship between PWV and diastolic dysfunction of HFpEF is significant.