Pediatric Interscalen Brichial Plexus Block With Different Doses Of Ropivacaine

Objective The aim of this study was to compare the efficacy of different does of ropivacaine for pediatric interscalene brachial plexus block.Methods 40 aged from 2 to 12 years old children, scheduled for upper extremity surgery, were divided into two equal groups randomly:0.375% ropivacaine group (group A) and 0.25% ropivacaine group (group B). Children were under close monitoring and intravenous 2mg/kg of ketamine in the operating room, while continuous intravenous infusion of propofol 2～4mg.kg-1.h-1 to maintain calm. When the pediatrics lost consciousness, interscalene brachial plexus block was performed under ultrasound-guided combined nerve stimulator, A group using 0.375% ropivacaine 0.5ml/kg, group B using 0.25% ropivacaine 0.5ml/kg. Block performance time, the quality of anesthesia, recovery time, the duration of block, the used of painkillers in postoperative and the score of FLACC and Ramsay postoperative 2h,4h,6h, 10h,12h;nerve injury and other complicationins were recorded.Results 1.There was no significant difference in two groups’ age,height,weight and surgical date (P>0.05).2.There was no significant difference in two groups’ operative time, the total amount of propofol and ketamine (P>0.05) 3. Each time point of MAP, HR and RR in two groups has no significant difference (P>0.05).4. The duration of block was longer in group A than in group B (P<0.05).5. Two groups of success rate were 100%.6. In postoperative 10h, the score of FLACC and Ramsay was significant difference in two groups (P<0.05); in the other times the score of FLACC and Ramsay had no significant difference in two groups (P>0.05).7. There was no significant difference in the use of painkillers after surgery in two groups (P> 0.05).Conclusion Ultrasound-guided pediatric interscalene brachial plexus block with 0.375% and 0.25% ropivacaine can provide effective and safety block, no pediatric patients developed block-related complications in each group. The doses of 0.375% ropivacaine can provide longer the duration of anesthesia.