The Clinical Characters And Significance Of The Change Of Hemorrheology For Ischemic Colitis Patients

Part â… :The Comparison of Clinical Characters of Ischemic Colitis and Ulcerative ColitisObjective:Compare the clinical character of Ischemic Colitis (IC) and Ulcerative Colitis (UC), this is to increase the diagnostic accuracy.Methods:Choose43IC patients and36patients of Gastroenterology Department of Minhang District Central Hospital, Affiliatel to Shanghai institute of Health Sciences during Jan2008through Jun2011, compare and analyze the clinical character.Results:Two groups has the statistics meaning in terms of gender, age, course of disease and source of disease (P<0.05); more aged women in IC group, with short course of disease, and also with cardiovascular disease (29/43,67.0%). The CRP of IC group is higher than UC, PLT is lower than UC group (P<0.05).There is more sigmoid colon in IC group and less rectum,regional limitation of pathological changes, with longitudinal or irregular Ulcer, the focus is cured quickly, with more mucositis pathology. Yet the UC group pathological changes were originated from rectum and implicated to the whole intestinal surface, with continue pathological change, with more needle-point type geographic Ulcer, with cryptitis and abscess.Conclusion:It is good to differentiate the diagnosis of IC and UC when we comparing the endoscope pathological image, laboratory data, source of disease and the cure of focus in short term.Part â…¡:Clinical Significance of the Change of Hemorrheology, PLT and CRP for Ischemic Colitis PatientsObjective:To analyze the significance of changes of hemorrheology, PLT and CRP for Ischemic colitis patients.Methods:1. Comparative analysis of changes of hemorrheology, PLT and CRP for40cases of Ischemic colitis patients (IC Group) and30cases of healthy people (Control Group).2. Investigate the change character of hemorrheology, PLT and CRP for Ischemic colitis patients.Results:1. The Plasma viscosity and CRP of IC group are much higher than control group which has statistics significance (P<0.05) 2. The youth group plasma viscosity compares to elderly group has statistics significance.3. The is significant difference of blood viscosity between Ischemic colitis patients who has fundamental disease and patients without fundamental disease.Conclusion:1. The plasma viscosity of Ischemic colitis patients increase significantly which has the risk of thrombus, CRP of IC group is much higher than control groups, which is due to the infection by damage of intestinal mucosa barrier and ectopia of intestinal germ. Earlier treatment including anti-freezing and anti-infection to Ischemic colitis patients is necessary.2. Hypertension, diabetes, hyperlipemia, coronary or cerebral infarction has more risk to have Ischemic colitis, regular treatment to control blood pressure, glucose, lipemia and improve the blood supply of heart and brain, is helpful to reduce the blood viscosity and to improve the IC prognosis.