Permanent¹²⁵I Seeds Implantation Brachytherapy For Prostate Cancer By Guidance Of Ultrasound

Objective:To evaluate the clinical application and complications of permanent125I brachytherapy in patients with prostate cancer. And access the feasibility of this treatment in different risk factor patients.Methods:40prostate cancer patients underwent3-dimensional125I seeds implantation brachytherapy with transrectal ultrasound-guide.40patients were divided into three groups according to their risk factors:low risk factor group, median risk factor group and high risk factor group.Results40patients with single125I brachytherapy mean blood serum PSA were(18.72±27.74) ng/ml before treatment and (0.16±0.35) ng/ml three months later after treatment with a significant difference(P<0.01). There were significant difference (P<0.01) between preoperational PSA and post operational PSA in three groups (P<0.01).And post operational PSA were insignificant difference(P>0.05) in three groups respectively.Conclusions Brachytherapy with125I seeds implantation guided by transrectal ultrasound is a safe, minimally invasive and effective treatment for prostate cancer patients...