Local Injury Of Endometrium For Repeatedly Implantation Failed To Improve The Effectiveness And The Receptivity Of Endometrium:a Meta-analysis

Objective:To local Injury of Endometrium for the clinical application of repeated implantation failure to provide reliable evidence. This article through to published at home and abroad of local Injury of Endometrium for repeated implantation failure Meta analyses of clinical research. Of in vitro fertilization embryo transfer (IVF/ICSI) of embryos implantation rate, clinical pregnancy rate and abortion rate, live births rate, make more objective and reliable evaluation, provide the basis for clinical. Methods: Comprehensive search PubMed, EMCC, the Cochrane library, biomedical foreign full-text service system, CNKI, VIP journals of science and technology and digital knowledge platform database of ten thousand to2013, all the relevant information,into the group and not blow gently blow gently surgery for embryonic cultivation of good quality and repeated failure of randomized controlled trials (RCT) with5references and not random (prospective study) with3references, the Meta analysis into the literature by using Revman5.1software included in the study results are homogeneity test was performed to find Meta analysis and data merging. Results:A total of eight articles were included in this study, including six references in English and Chinese with two references, on a total of861cases of patients with combined。Including406local Injury of endometrium group, controlled studies455people.local Injury of Endometrium can significantly increase the embryo implantation rate [RR=1.81,95%CI (1.48,2.23), P<0.00001]; Also significantly improves the pregnancy rate [RR=1.81,95%CI (1.49,2.19), P><0.00001];and a live birth rate [RR=1.80,95%CI (1.37,2.37), P<0.0001],but the miscarriage rate [RR=0.84,95%CI (0.49,1.44), P=0.53] and3studies have shown that comparing the two groups had no significant effect endometrial thicknesshad no effect(P>0.05). Conclusion:Local Injury of endometrium of infertile women for repeated implantation failure can improve the receptivity.improve the embryo implantation rate, clinical pregnancy rate and live birth rates. This operation is clinically feasible.