To Analysis The Effect About The Evaluation Of Curative Effect Of IL-1β And TNF-a In Pulsed Radiofrequency Treatment Of Herpes Zoster Neuralgia

Objective:In order to explore the new treatments, we determined the lever of IL-1β、 TNF-a and VAS score changes of preoperative and postoperative to observe the curative effect of pulsed radiofrequency treatment of herpes zoster neuralgia. Methods:The15patients with zoster associated pain were evaluated IL-1β、TNF-a and VAS before and after the pulsed radiofrequency treatments. The results were analysis by SPSS17.0statistics. Results:There are significant difference in IL-1β、TNF-a and VAS scores of HP and PHN patients before and after the pulsed radiofrequency treatments (p<0.05). There are evident difference in IL-1β、TNF-a between the HP group and Normal control group (p<0.05). There are significant correlation between IL-1β、TNF-a and VAS scores before and after the pulsed radiofrequency treatments (p<0.05). Conclusion:The anti-inflammatory cytokine levels are associated with the pain of herpes zoster-the higher the anti-inflammatory cytokine level is, the higher the pain score. The recent effect of pulsed radiofrequency treatment of herpes zoster pain is remarkable.