Assessment Of Regional Myocardium Function Of Left Ventricular In Children At Acute Stage Of Kawasaki Disease By Speckle Tracking Imaging

Objective: To evaluate the feature of regional myocardium function of leftventricular in children of with Kawasaki disease by speckle tracking imaging.Methods: In this study,31cases with the first stage，the sencond stage, thethird stage Kawasaki disease were chosen, and23normal children were selected as comparison. Two-dimensional dynamics grayscale imaging was obtained inapical four chamber, apical two chamber and apical three chamber. Then measured the long axis of the regional left ventricular myocardial strain in18paragraphes, that the peak systolic strain rate (PSS) and post systolic index (PSI).Results:1. Each group EF, FS and HR was no significant difference comparedwith each other.2. In the first phase group, PSS of most left ventricular myocardialsegments was lower than the normal group (P<0.05). Compared with the normalgroup, PSS in the baspost, basantsept walls of the second stage group are statisticallysignificant difference (P<0.05), In the sencond stage, PSS in higher than those of thefirst group, baspost, baslat walls and in the midpost, midlat walls are statisticallysignificant difference (P<0.05). Compared with the first stage Ⅰ, PSS in mostsegments wall of KD Phase Ⅲ increased significantly values (P<0.05).3.In the firstphase group, PSI>0the number of segments increased than normal group (P<0.01).In the second phase group, PSI>0the number of segments increased than normalgroup (P<0.01). comparison with the Phase I and Phase Ⅱ, Phase Ⅲ PSI>0thenumber of segments were significantly reduced, the difference was statisticallysignificant. In the first phase group, PSI values are higher (median=13) than normalcontrol group (P<0.01). The phase Ⅱ, PSI values (median=10) was significantlyhigher compared with normal group, the difference was statistically significant (P <0.01). comparison with PhaseⅠ and Phase Ⅱ, PhaseⅢ PSIvalues (median=3) weresignificantly reduced the difference was statistically significant (P <0.01).4.In thefirst phase, PSS of all myocardial segments with coronary artery dilatation lower thanKD group without coronary artery dilatation, was not statistically significant (P>0.05). The inter-observer variation coefficient of PSI and PSS was7%, the variationcoefficient in the PSI and PSS of the observer was4%.Conclusions: KD could lead any regional myocardium of the left ventricular todysfunction, PSS and PSI could accurately reflect the imperceptibility changes. Therelationship between the degree of myocardial dysfunction and coronary artery lesionswas not...