Insulin-like Growth Factor-1and Chronic Complications Of Diabetes

Insulin-like growth factor-1(IGF-1) is a kind of protein polypeptidewhich widely exists in the body tissue and its structure and functions aresimilar to the insulin. IGF-1involves in many pathological andphysiological process. IGF-1affects the occurrence and development ofchronic complications of heart, brain, kidney, peripheral nerve in thediabetics through multiple pathways. Studying the mechanism of IGF-1will provide new predictors and therapeutic targets for the preventivetreatment of chronic complications of diabetes...