Kinetics Of Benign Prostatic Hyperplasia Urinary Detrusor Contraction Abnormalities

Object:Objective To study the value of the preoperative detrusor contractility to the outcome assessment of prostatectomy for benign prostatic hyperplasia(BPH). Methods A total of58patients with BPH were analyzed. Their ages ranged from62to82years with a mean of69years. All patients under went urodynamic study to confirm a diagnosis of B00preoperatively. Further more, their B00was not caused by nervous, endocrine or other diseases. Pateints were divided into two groups based on maximum detrusor contractility. Group I(n=33, BPH with maximum detrusor contractility≥40cm H20,1cmH20=0.098kPa) underwent TURP or open surgery, respectively. Group Ⅱ(n=25, BPH with maximum) detrusor contractility≤20cmH20) underwent TURP and suprapubic punctural cystostamy simultaneously, the bladder fistula was kept open continuously for at least two weeks postoperatively. The difference in outcome between the two groups was assessed by using urodynamic parameters including maximum detrusor contractility, Qmax and residual urine at one and three months postoperatively respectively. Student’s t-test was used to compare the result for normally distributed data and Wilcoxon’s signed-ranks test for skewed data in this study. Results There was significant difference in preoperative maximum contractility,Qmax between group Ⅰ and group Ⅱ (75.55±28.66cm H20)vs (19.52±4.99cmH2O)(P<0.01)(6.76±2.15ml/s)vs(3.12±1.23)ml/s(P<0.05) respectively. Although there was significant difference at one month postoperatively in Qmax(15.24±2.48)ml/s vs(13.40±2.44)ml/s (P<0.05), no significant difference was found in Qmax between the two groups after three months(15.45±1.93ml/s) vs(14.84±1.59) ml/s (P>0.05). Conclusions The Qmax may improve and the impaired detrusor recovered gradually after the BOO was removed. Performing an operation on patients with BOO accompanied with detrusor underactivity may be useful to recover detrusor contractility.