A Research On Modified Jinkui Renshen Tang And Shenqi Wan Treatment For Crohn’s Disease

Crohn’s disease, clinically manifested by general symptoms such as abdominal pain, diarrhea, abdominal mass, anal fistula, developmental retardation and so on, is a type of chronic granulomatous inflammatory disorder, which may induce damages in every part of gastric and intestinal duct, even causes extra-intestinal lesions. The disease is difficult to be cured and frequently reappears with poor prognosis, so far no specific drug or treatment method was found around the world, currently the treatment only aims to relive symptoms.In western medicine, an accordant understanding on its diagnostic criteria has been achieved, but etiology and pathogenesis still remain unclear. Medicine is the main treatment while nutrition support and surgery also play a part in the treatment. Syndrome differentiation of Chinese medicine is taken according to the stages of disease and clinical characteristics,the main treatment such as internal treatment and external treatment is applied separately according to the different stages of disease, and other therapies including herbal enema, acupuncture and moxibustion, surgery also could be used. The integrated treatment of Chinese and western medicine has got a certain effect in inducing and maintaining relief of disease, preventing complications and improving life quality.According to the supervisor’s experience, the combination of formula Renshen Tang and Shenqi Wan has a good result on the Crohn’s disease. Further intensive research has been conducted on this combined formula treatment for Crohn’s disease under the supervisor’s guidance and summarization of other Chinese medicine classics. The research clearly proposes that main cause for the disease is deficiency of both spleen and kidney and weak healthy qi(the root), pathogenic factors such as phlegm and dampness are produced then (the superficial), so the character of disease is the combination of deficient root and excessive superficial. The research also points out that the treatment according to syndrome differentiation for Crohn’s disease should be based on the modification of Renshen Tang and Shenqi Wan due to their combined functions "Tonifying and nourishing spleen and kidney, removing blood stasis and resolving phlegm". It not only supplies a method for the research on pathogenesis and treatment formulas and herbs, but also identifies the practical significance of "Synopsis of Golden Chamber"in nowadays.