The Macular Micro Vision And Macular Pigment Optical Density Of Age-related Macular Degengeration

Objective Using the vision module and macular pigment densitymodule of the French Metrovision MonPack3visual surveillance systemaccordingly to have detection in patients with age-related maculardegeneration. To explore the mumerical result of macular micro vision andmacular pigment density and its correlation in the different types of ARMDabout the elderly people, we can use the influence of classification of thedisease to provide basis for the follow-up inspection.Methods The patients who confirmed by clinical diagnosis andclassification with age-related macular disease degeneration take theexamination of the macular vision and pigment in fundus the by theMonPack3visual surveillance system. Judging and recording the scotomanumber,stability of fixation,central focus condition,mean deficit of microvisual field and the density of macular pigment.Different diseases, thestability of fixation and scotoma number using Wilcoxon test; Theconection between the corrected visual acuity and macular micro visiondefects and macular pigment density described by Spearman rank correlation analysis;The diversity of macular pigment density and macularmicro vision defects in different ARMD types descrbed by one-wayANOVA analysis of variance.All of them operation in the SASV8greenversion.Results17patients with ARMD28eyes, exudative ARMD19eyes(male9, female10), fixation stabe10eyes, relatively stable3eyes,unstable6eyes; Atrophy ARMD9eyes (male6, female3), fixation stabe6eyes, relatively stable2eyes, unstable1eye;28eyes are all central focuseye. There was no significant difference of the stability between differenttypes of ARMD (chi-square=0.8370, P=0.3621), even no obviouscorrelation with best corrected vision (chi-square=1.6560, P=0.4369).There is no obvious difference in different gender (chi-square=1.7398, P=0.1872). Best corrected visual acuity and ARMD eye macular microaverage visual defect degree have no obvious correlation (CC=-0.14934, P=0.4482), but significant correlation (CC=0.42578, P=0.0239) withmacular pigment density. The two different types of ARMD eyes have nosignificant difference in the scotoma number (chi-square=0.448, P=0.5048),the macular average defect value (F=0.26, P=0.6118),themacular pigment density(F=2.24, P=0.1469).Conclusion The two types of exudative and atrophy ARMD nosignificant difference in macular micro vision defect degree and macularpigment density.The visual stability of the patients have no statistical significance with the lesion type, best corrected visual acuity and thegender of ARMD.There is a positive correlation between the best correctedvisual acuity and macular pigment density, but no obvious correlationbetween the best corrected visual acuity and macular micro vision and.Afterwards,not only use the macular micro vision and macular pigmentdensity but also combine the clinicn and other examination to diagnosis andfollow up the sub-type of ARMD.