Prospective Study On The Effection Of Symptomatology Of Irritable Bowel Syndrome By Intervening The Intestinal Flora

ObjectiveTo explore the relationship Between imbalance of intestinal flora and IBS by observing whether intervention of the intestinal flora can prevent and relief the irritable bowel syndrome subsequently.Methods(1)100patients who suffered diarrhea-predominant IBS (IBS-D) from december2010to december2011were divided into two groups randomly after being cured by conventional treatment, intervene group and observation group.(2) The intestinal flora were monitored every4-6weeks by checking the fecal bacteria. As for those who appears intestinal flora imbalance, the intervene group will give treatment and the observation group will stay for further observation.(3)When symptoms appear,record the patients’ IBS symptomatology score.Otherwise,record no symptoms.ResultsThere are85patients finished the test according to the requirements.①The recurrence rate of observation group is higher than intervene group (P<0.05).②In the observation group,total symptomatic scores、abdominal pain time、abdominal pain frequency and abdominal bloating proportion was higher than those in the intervene group. The difference between two groups was significant(P<0.05), but there were no significant difference in the rate of exceptional shape of stool, exceptional defecation and sticky fluid and stool (P>0.05).③The recurrence rate of patients with intestinal flora imbalance is higher than the patients without intestinal flora imbalance (P<0.05)ConclusionThe imbalance of intestinal flora related to IBS, it maybe one of the important causes of IB S.Therefore, restoring the normal intestinal flora contributes to the prevention of IBS.