Tantalum And Peek Materials Of Intervertebral Fusion Analysis Recent Curative Effect Of Treatment Of Lumbar Intervertebral Disc Protrusion

BackgroundLumbar disc herniation is the ordinary and frequently-occurring disease inorthopaedic，and The most common reason for Which caused Lumbocrural pai. It ismajor because that the spinal nerve root oppressed by the degeneration ofintervertebral disc tissue.with the effect of outside factors, disc annular, comes fromdifferent parts of the lumba (Nucleus pulposus, fiber ring and the cartilageplate),especily for Nucleus pulposus, was brusted after had varying degrees ofdegenerative change. Then the nucleus pulposus tissue prominent (or emergence)from the rupture in the rear or spinal canal, and oppress the spinal nerve. Because ofthese,a series of clinical symptoms, such as the waist pain, the numb or pains of thelower limbs in one or double sides have taken place. The incidence of Lumbar discherniation is most common in L4/L5、L/S1,which ois almost95%. The current studyhas shown that, there are54%of people who has lumbocrural pain worked in the lightlabor, and the percentage of those worked in the heavy labor is70%.40%of thesepatients would be developed into lumbar intervertebral disc protrusion and affectedtheir daily physiological activities. According to the record, it had been discribed for"sciatica" two thousand years ago. Foreign scholars, Mixter and Barr had alreadydetermined that the lumbar intervertebral disc protrusion was the main reasons of"sciatica" in1934. It is common in young adults of the disease. The trend of the agefor this disease is becomes older than before. People whose horsetail nerve wasinguried would have disability in gatism,even be likely to paraplegia. So it wouldhave a serious influence on normal physiological activities of patients. Recently, wecan make a clear diagnosis through the patients of detailed history, careful physical examination and imaging of the auxiliary. With the rapid development of molecularbiology, cell biology, and others auxiliary discipline, we had already gradually clearthat the mechanism of intervertebral disc degeneration is lumbar intervertebral discprotrusion. Intervertebral disc degeneration refers to the normal structure ofintervertebral disc has disappeared, And showed in progressive fibrosis, which isspecific display in the following process: the gradually disappearing sample gelnucleus pulposus, fibrosis and boundaries of nucleus pulposus disappeared, thedisorder of layered structure fibrosis, and the compound of fibrosis. The mechanismof intervertebral disc degeneration is very complicated, there is no definite conclusionin present study, most researchers concluded that intervertebral disc degeneration hadan relationship with biomechanics, intervertebral disc nutrition, immune, cellapoptosis, and genetic factors in many aspects from the relevant researches. It isbecause all of these can make changes in intervertebral disc cells and extracellularmatrix components, and the changes of intervertebral disc cells and extracellularmatrix is the direct reason for the loss of its mechanical characteristics. Intervertebraldisc is a kind of fiber knot hoof tissue without avascular, which is disc-shaped,elasticity can be Can dispersed and buffered the the load of spine. And it plays animportant role In supportting and motoring function of spine. Inervertebral discis composed of the middle Annulus Fibrous, the Nucleus Pulposus (Annulus Fibrousis divided into two parts of layer nand the inner, and located in the external of middlepart, Nu cleus Pulposus is located in the inner of middle part), the transition regionbetween Annulus Fibrous and Nucleus Pulposus and the Cartilage End–Plate.Because of the largest non-avascular tissue in our body and under huge pressure load,so intervertebral disc is likely to degenerated. There are two kinds of main treatmentin intervertebral disc degeneration, conservative treatment and surgical treatment. Theconservative treatment is consist of having a rest on bed, medication, physicaltherapy, the injections with hormone,and so on. But all of these treatment can onlyimprove the clinical symptoms, and to completely cure the disease, it can not be.In the middle of1940s, the concept of posterior lumbar intervertebral fusion(PLIF) was introduced into clinic by Jaslow and Clowoud, the basic principle coversthe following parts: providing the mechanical stability, retaining the original height of intervertebral disc, strutting the intervertebral foramen. There are about70years inSurgical treatment of LDH in our country. And53years had past since the first caseof surgical treatment published by Fang Xianzhi in1952. With the development ofmedical and health undertakings in our country, the operation methods have beenmore and more improving and normative. At present, the surgery of plif has becomethe mainstream for the treatment of LDH. With the development of tissue engineering,physics, biology, mechanics and other auxiliary discipline, more and more differentorganizations materials of intervertebral cage are been used to maintain theintervertebral height, prevent operation stage and collapse, resist rotationof spine. theclinical mainstream application of cage is made of peek material now, and tantalummaterial cage has gradually applied to the clinical surgery. There is no clearcomparison of superiority between the two kinds of material cage in intraoperativeand postoperative. In this experiment, we compared the two kinds of material of thecage in surgery, blood loss, and on the basis of ODI score, VAS score to judge theoperation effect, postoperative follow-up which was based on the assessment ofintervertebral fusion by X-ray SUK method. So we can provide the basis for clinicalselection.ObjectiveWe are aim to make a comparison and analysis about the curative effect of twokinds of material cage in LDH PLIF treatment, and provide reference for clinic.MethodsSelecting60cases of patients with lumbar disc prolapse, and performingoperations on all of them by the methods of PLIF combined with pedicle screwsystem stable internal fixation.30cases are maked in an application of Tantalum, andthe others are Peek material cage. Then making a comparasion of two groups byoperation time, blood loss, and evaluating the effect of surgery on the basis of ODI、VAS scoring methods, postoperative follow-up about1-6months. Observing theIntervertebral fusion by SUK method according to the postoperative (1month,3 months,6months) X-ray image. Studying the curative effect of nearby and forward.ResultsThe surgery of all cases were completed successfully,so as the follow-up. It wasabout6months for each patients.,there is no statistically significant difference in age,gender of conventional in contrast groups. So did the operation time, surgical bloodloss.The scores of VAS, ODI in postoperative back pain and lower limb symptomswere significantly lower than groups of preoperative. Comparing differences betweentwo groups,there was no statistical significance. Comparied intervertebral disc heightof Preoperative with postoperative,there exsited statistical significance in bothConventional and contrasting group,but had no statistical significance between twogroups. The intervertebral fusion rate of two groups achieves above90%ConclusionThere exsits no significant differences of two materials kinds of intervertebralcage in improving the symptoms of patients or the satisfactory clinical effect.