| ObjectiveSummarize different syndromes irritable bowel syndrome patients with clinical symptoms of diarrhea, explore the relationship between age and body mass index as well as the symptoms and syndromes. Collect patients and normal spleen dampness synchronous colonic manometry dynamic results, analyze the relationship between the colon and the dynamics indicators of TCM.MethodsPatients suspected of diarrhea-predominant irritable bowel syndrome (ISB-D) performed colonoscopy and other related examination to exclude organic disease, identified as ISB-D patients. With the assistance of colonoscopy, the colon manometry tube placed in the colon of patients with spleen dampness type, collecting main symptoms, minor symptoms and related manometry data. Correlation analysis SPSS statistical software appears rule spleen dampness syndrome and colonic motility pressure wave data was last used.ResultsAge of onset ISB-D between different syndromes, BMI was not statistically significant (P>0.05). The study is based on different time periods, namely in the afternoon, night and morning, the power indicator on the different sections of the colon contrast and compare their normal and IBS-D patients with spleen dampness, such as the number of peaks and amplitudeThe first is the number of normal peak contrast, the afternoon is the transverse colon>descending colon>ascending colon>sigmoid colon; night, ascending colon>sigmoid colon>transverse colon>descending colon; morning, transverse colon>ascending colon>sigmoid colon>descending colon. Overall, the day’s peak numbers are ascending colon>transverse>sigmoid colon> descending colon. Amplitude comparison:in the afternoon, descending colon>sigmoid colon>ascending colon> transverse colon; night, sigmoid colon>ascending colon>transverse colon>descending colon; morning, sigmoid colon>descending colon>transverse colon>ascending colon; Overall, sigmoid colon> descending colon>1colon>transverse colonFrequency comparison:in the afternoon, descending colon>transverse colon>ascending colon>sigmoid colon; night, transverse colon>descending colon>ascending colon>sigmoid colon; morning, descending colon>sigmoid colon>transverse colon>ascending colon; Overall, the descending colon>sigmoid colon>transverse>ascending colonColonic motility contrast:sigmoid colon>descending colon> ascending colon> transverse colon (p<0.05).Patients in the colon at different time zone change is consistent with the normal. But the comparison with the normal, it is the peak number amplitude, frequency, and colonic motility are high.24hours of normal colonic motility was896.9+34.4, patients with colonic motility was1158.1±38.7, there were statistically significant differences between the two (p <0.05).Normal fasting2h postprandial colonic motility in contrast to the more obvious.2h represents normal fasting colonic motility in the resting condition, which is normal colonic motility.1h postprandial colonic motility related indicators compared with fasting1h, is growing exponentially, then2h postprandial data somewhat lower, but still higher than normal levels. Patients with higher than normal. However, the magnitude of postprandial rise1h, the patient is lower than the normal person. The number and frequency of the peak two indicators, compared with patients with postprandial2h postprandial1h, a slight rise.Comparison with2h before bedtime and2h after wake up, the latter larger, the difference is mainly reflected in the number and amplitude of the peaks. Although the frequency increases, but without the first two big rise. Patients compared with normal subjects, consistent with changes in the situation. But the indicators independent comparison, p>0.05, little difference between the two was not statistically significant.Conclusion:The molitity of each spleen dampness syndrome patients’colonic segment is similar with normal variation, but the change of extent and range is larger than the normal, which maybe the reason of bloating and pain.24hours colonic manometry is well wih prospect in the diagnosis of dysfunction of intestinal diseases... |