| ObjectiveMenstrual endometrium is generated and accepted part of the embryo. Endometrial lesions is a common pathological process in the development of obstetrics and gynecology diseases, that leads to diseases such as menstrual quantity is little hypomenorrhea and sterility. So the research of endometrial repair is of great significance for the woman’s menstrual disorders such as infertility. This topic through the literature research of clinical research and experimental research on Kidney drug abortion of endometrial repair after impact, And to analyze its possible mechanism,, In order to offer clinical thought to promote restoration of the endometrium, rich clinical treatment of traditional Chinese medicine.MethodsThis topic points clinical research literature research animal experiments of three parts. This class literature research mainly from two aspects of Chinese and western medicine system current situation of research on endometrial injury repair.clinical research:it is observation of curative effect, use the principle of random、control, Divided subjectsinto the treatment group、blank group、control group of Chinese traditional medicine、 western medicine control group. On abortion vaginal bleeding time、endometrial thickness、the parameters of the uterine artery blood flow、endometrial three lines、Menstruation recovery, assessment of Convection postpartum endometrial repair kidney medicine clinical curative effect、empirical study:It observes the objective indicators,uses the principle of random、control, Divided model rats into the treatment group、blank group、control group of Chinese traditional medicine、western medicine control group. On abortion VEGF、 estrogen、progestin, assessment of kidney medicine convection postpartum endometrial repair mechanism.ResultsLiterature research of Chinese and western medicine research status of comprehensive study of endometrial lesions, found the train of thought for the research of this topic. Clinical studies:1、Four groups of patients with postoperative vaginal bleeding time:the treatment group(4.72±1.27d)、blank group (6.42±1.39d)、western medicine control group (4.56±1.04d)、control group of Chinese traditional medicine(6.37±1.42d). Traditional the treatment group compared with blank group, the difference have statistically significant (P<0.01)。Traditional the treatment group compared withwestern medicine group, the difference was no statistically significant (P>0.05)。Traditional the treatment group compared with control group of Chinese traditional medicine, the difference was statistically significant (P<0.01)。2、Four groups of14days postoperatively in patients with endometrial thickness of uterine artery blood flow index:the treatment group (8.61±1.33mm)、 PI (1.17±0.27)、RI (0.61±+0.07)、blank group (5.84±1.86mm)、PI (2.29±0.58) RI (0.89±0.14)、western medicine control group (8.72±1.12mm)、PI (2.03±0.52)、RI (0.91±0.15)、control group of Chinese traditional medicine (6.10±1.56mm)、PI(1.24±0.23)、RI(0.59±0.08)。The treatment group compared with the western medicine control group, endometrial thickness there was no statistically significant difference (P>0.05), with the blank group、Gontrol group of Chinese traditional medicine, endometrial thickness there was statistically significant difference (P<0.05)。The treatment group uterine artery blood flow index compared with western medicine control group、 blank group、control group of Chinese traditional medicine, the difference was statistically significant (P<0.01)。3、Four groups of21days postoperatively in patients with endometrial thickness of uterine artery blood flow index: the treatment group (9.72±1.18mm)、PI (1.08±0.25)、RI (0.64±0.08). blank group(8.26±1.45mm)、PI (2.20±0.45)、RI (0.84±0.11)、western medicine control group (9.50±1.29mm)、PI (1.90±0.29)、RI (0.86±0.10)、control group of Chinese traditional medicine (7.79±0.92mm)、PI (1.07±0.24)、 RI(0.59±0.06)。The treatment group compared with the western medicine control group, endometrial thickness there was no statistically significant difference (P>0.05), with the blank group、control group of Chinese traditional medicine, endometrial thickness there was statistically significant difference (P<0.05)。The treatment group uterine artery blood flow index compared with western medicine group.. blank group, the difference has statistically significant (P<0.01)。The treatment group uterine artery blood flow index compared with control group of Chinese traditional medicine, the difference was no statistically significant (p>0.05)。4、endometrial three lines of four groups:The treatment group has15people, accounts for83.30。 blank group has8people, accounts for42.10。 western medicine control group has11people, accounts for61.10。control group of Chinese traditional medicine has9people, accounts for47.40。The treatment group compared with blank group、control group of Chinese traditional medicine, the difference have statistically significant (p<0.05)。The treatment group compared with western medicine group, the difference was no statistically significant (p>0.05)。5、menstruation recovery of four groups:The first menstrual period of time of The treatment group (28.56±3.41d)、blank group (38.50±7.53d)、 western medicine control group (30.50±2.70d)、control group of Chinese traditional medicine (39.06±7.64d)。The treatment group compared with blank group、control group of Chinese traditional medicine, the difference has statistically significant (p<0.05)。The treatment group compared with western medicine group, the difference was no statistically significant (p>0.05)。 The second menstrual period of time of The treatment group (31.72±3.14d)、 blank group (37.11±7.38d)、western medicine control group (35.44±5.38d)、 control group of Chinese traditional medicine (40.78±3.95d)。The treatment group compared with western medicine control group、blank group、control group of Chinese traditional medicine, the difference was statistically significant (P<0.05)。experimental results:1、Four groups of model rat’s VEGF levels:The treatment group (0.53±0.09COD)、blank group(0.33±0.27COD). western medicine control group (0.24±0.11COD)、control group of Chinese traditional medicine (0.45±0.13COD).The treatment group compared with western medicine control group、blank group, the difference have statistically significant (P<0.05)。The treatment group compared with control group of Chinese traditional medicine, the difference was no statistically significant (p>0.05)。2、Four groups of model rat’s estrogen level:The treatment group (232.68±21.22pmol/1)、blank group(166.58+36.99pmol/1)、 western medicine control group(235.20±17.16pmol/1)、control group of Chinese traditional medicine (200.34±31.19pmol/1). The treatment group compared with blank group、control group of Chinese traditional medicine, the difference was statistically significant (P<0.01)。The treatment group compared with western medicine control group, the difference was no statistically significant (p>0.05)。3、Four groups of model rat’s progestin level:The treatment group (9.78±12.39ng/ml)、blank group (18.53±15.50ng/ml)、western medicine control group (22.48±15.57ng/ml)、control group of Chinese traditional medicine (17.58±13.37ng/ml).The treatment group compared with western medicine control group、blank group, the difference was statistically significant (P<0.05)。The treatment group compared with control group of Chinese traditional medicine, the difference was no statistically significant (p>0.05).ConclusionExperimental results:Kidney medicine can shorten the time of vaginal bleeding after abortion, can promote the endometrial thickening, can Improve the uterine artery blood flow, can promote the menstrual period。Experimental results:Kidney medicine can improve the abortion VEGF levels in rats, can improve the abortion estrogen levels in rats, and can not affect the progesterone decrease。Kidney medicine can improve the body’s estrogen levels, prompting abortion surgery endometrial thickening, thus shortening the time of vaginal bleeding after abortion, reduce the postoperative infection, promote restoration of the endometrium。Kidney medicine can improve the body content of VEGF and uterine blood flow, prompted uterine angiogenesis, also shortened the time of vaginal bleeding after abortion,, promoted the endometrial repair。Kidney medicine does not affect the body a decrease in the level of progesterone, prompted postoperative period in a timely manner after the abortion, and establish a normal menstrual cycle in a timely manner。... |
PDF Full Text Request