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The Application Value Assessment Of C-arm CT On TACE Therapy To Hepatocellular Carcinoma

Posted on:2014-12-07Degree:MasterType:Thesis
Country:ChinaCandidate:X S YaoFull Text:PDF
GTID:2284330431976235Subject:Imaging and nuclear medicine
Abstract/Summary:PDF Full Text Request
[Objective] To assess the application value of CCT on the TACE therapy to hepatocellular carcinoma.[Method] CCT scans were performed to80hepatocellular carcinoma patients under TACE therapy between Sep.2012and Mar.2013in the hospital. The CCT plain scan image, artery early phase image, parenchymal phase image and afterwards treatment image were read and evaluated. The number of the focus, feeding artery status before TACE therapy and the residual carcinoma focus, lipiodol deposition, feeding artery embolism etc. after therapy were observed. The x-ray radiation doses throughout the process of detection and therapy were recorded and compared with those from the group not received CCT scan therapy.[Results]139focuses were found in these80patients received CCT scan.5more focuses in4patients and2more focuses in2patients received CCT scan were found compared to64spiral CT scan and routine DSA respectively. Before TACE therapy, CCT scan showed clear image of the feeding artery to131focuses in77patients, which facilitated the super-selective intubation therapy using microcatheter in28patients among these (36.36%). Abnormal feeding artery to focuses were found in4patients and abnormal feeding artery course was imaged clearly in1patient. After TACE therapy, the therapeutic effect of CCT scan on128focuses was assessed satisfactory in75patients (128/139,92.09%).78,29and21of them were found have less, moderate and more residual focuses respectively,64,39and25of them were found dense, medium and thin lipiodol deposition respectively. Blood-feeding were found significantly decreased in101of them and no significantly decreased in27of them respectively after embolotherapy. The average x-ray radiation dose on the skin was393.18mGy in the CCT scan group while the average x-ray radiation dose on the skin was401.05mGy in the control group. Statistical significance wasn’t found between these two mean values using independent sample t test (t=0.355, P=0.723).[Conclusions]In the process of TACE therapy to hepatocellular carcinoma, CCT scan is helpful in detecting carcinoma focuses, imaging feeding artery, abnormal feeding artery and abnormal artery course, evaluating residual focuses, lipiodol deposition, feeding artery embolism immediately after therapy. Furthermore, the x-ray radiation dose won’t be increased by CCT scan. There are broad prospects of applying CCT safely.
Keywords/Search Tags:C-arm CT, hepatocellular carcinoma, transarterial chemoembolization
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