Study Of Dimethylformamide To Work Crowd Health Effects And The Examination Cycle

Objective To reseach dimethylformamide(DMF) job crowd liver and kidneydysfunction and related indicators of abnormal situations, and even liver failure causesdeath. Learn DMF job crowd related disease development regulation. Explore DMF jobcrowd examination cycle and DMF poisoning sensitive indicator. Than providing theobjective foundation for the formulation occupational health surveillance programmes.METHODS Select a leather production enterprise as the research object, at thesame time with the company’s logistics non-contact DMF job crowd for reference, suchas collection of contact and non-contact crowd in2008-2012health care as a result, acomprehensive system to analyze the effect of DMF on the health of the understandingof DMF concentration and related parameters, the relationship between early determinesensitive index of DMF poisoning. Again according to the characteristics of frequentDMF acute poisoning, DMF operators in charge of the new hire the firm except for thestatutory pre-service physical examination, the mount guard after one week, two weeks,one month, three months, six months of health check, check after the project forcomprehensive analysis of alanine aminotransferase (ALT), aspertate aminotransferase(AST), gamma GGTP (gamma glutamyl transpeptidase)(gamma GT), and othersensitive biochemical indexes and indexes of blood routine, urine routine, the abnormalrate calculation, put forward the proposal to develop physical examination cycle. UsingSPSS12.0statistical package for the results were analyzed.RESULTS1. The mount guard after inspection personnel510people, a total of124people have complained of symptoms of digestive system, including nausea,86cases (16.86%), loss of appetite,35cases (6.86%), abdominal distension,27cases(8.63%), abdominal pain,30(5.88%). Followed by the respiratory system and nervoussystem symptoms, complained of a cough sore throat9cases (1.76%), insomnia, muchdream,6cases (1.18%), in addition there are15people complained of skin itching,15cases (2.94%). In addition to the2people found the arm of the skin rash, the rest of the staff are not seen obvious positive signs.2. The mount guard after liver function examination situation in different historicalperiods, as shown in the table12. As can be seen from the table, the mount guard after aweek to43people, the number of abnormal liver function abnormal rate was8.43%,and the mount guard after two weeks of76people, the total number of abnormal liverfunction abnormal rate was14.90%, the mount guard after a month to92, the totalnumber of abnormal liver function abnormal rate was18.04%. Mount guard after threemonths of112the number of abnormal liver function, the abnormal rate was21.96%,the mount guard after six months of118the total number of abnormal liver function,total abnormal rate was23.14%.3. The mount guard after the blood routine, urine routine, renal functionexamination situation compared with before mount guard, there was no statisticallysignificant difference.CONCLUSION1. DMF work personnel mount guard after a week can appearobvious abnormal liver function, and part of the personnel of abnormal liver functionbefore early in the digestive tract symptoms appeared, so early screening can findprofessional sensitive crowd.2. DMF acute poisoning to liver function index change with DMF concentration inair has obvious dose response relationship, take corresponding control measures toreduce the concentration of DMF in workshop air, is the most direct and effectivemethod.3. DMF occupational health plan remains to be further perfect, formulatereasonable sensitivity index and the appropriate physical examination cycle is helpful tothe early detection of occupational harm people, has a positive significance to safeguardworkers’ health.