Clinical Studies Of Coronary Artery Calcification And Coronary Atherectomy

Purpose:A preliminary study of coronary artery calcification imaging features and efficacy andsafety of. coronary atherectomy combine with PCI treat calcified lesions.Methods:Patients who had coronary artery calcification contrast the image in both verticalposition, and observe the level of balloon after10atm pre-expand, in order to analysisthe imaging features of coronary artery calcification.Based on random table numberdivided those that balloon was not fully inflate into coronary atherectomy combinedwith PCI group and PCI alone group, observation and analysis by intraoperativecomplications, immediate postoperative imaging, cardiovascular adverse events duringthe postoperative hospital stay and laboratory indicators. All statistical analyzes werecompleted by using SPSS17.0analysis software, P <0.05was considered statisticallysignificant difference test.Results:In this study,68patients were enrolled (from Liaoning Provincial People’s Hospital),coronary angiography showed that rates of left anterior descending artery calcification,left circumflex artery artery calcification and right coronary artery calcification were79.4%,13.2%and4.4%,7.3%with left mains coronary artery calcification, concluding that the rates of left anterior descending artery calcification occur rather thanother vessels. Observing the relationship between the vertical position image ofcalcification and level of balloon dilation in the two groups after data test, P <0.05considered statistically significant. Calcification used10atm predilation had1patientswith complication,above10atm predilation had5patients with complications,statisticalanalyzed between the two groups, P <0.05considered statistically significant, confirmedthat calcification with10atm predilation is safe and feasible. Based on random tablenumber divided those that balloon is not fully inflate into coronary atherectomycombined with PCI group and PCI alone group, of which the atherectomy combinedwith PCI group had11patients,19patients used PCI alone, the two groups were notsignificantly different basic information.(1) Comparing intraoperative complicationsbetween the two groups between the two groups was tested by the data, there was notstatistically significant, but the PCI alone treat the calcification are more likely occurvascular dissection due to the repeated large expansion of the balloon.(2) Comparingthe immediate postoperative image between the two groups, there was no significantdifference between the two groups in the TIMI level and postoperative narrow aftersurgery, but in trend of postoperative narrow atherectomy combined with PCI groupwas better than PCI group.(3) There was no significant difference between the twogroups on the acute, subacute thrombosis during hospitalization, malignantarrhythmias and other cardiovascular adverse events after statisticalanalysis.Confirming that atherectomy combined with PCI treat calcification did notincrase increase the incidence of adverse events.(4) Comparing the liver and kidneyfunction in ALT, AST, Cr, BUN after surgery by statistical analysis, the influence oftwo surgical methods liver and renal function was not statistically significant, and theliver and kidney function had not significant adverse effects in both groups.Conclusion:1. Coronary artery calcification more likely occured in left anterior descending artery.2.By two vertical position after the projection, the calcification images which werelocated in the center of artery are likely influence the intimal of artery. With10atm of balloon predilatation, there was no serious complications appear.10atm predilation treatcalcification was safe and feasible.3.Comparing with the treatment of calcification by PCI alone, the atherectomycombined with PCI can make the stand adherent completely, and get better immediateresults while reducing the restenosis rate, but also reduces the injury of artery by therepeated large expansion of the balloon. Treating calcification with10atm predilation issafe and feasible4. Confirming that compared with the treatment of calcification by PCI alone, theatherectomy combined with PCI did not increase the incidence of cardiovascularadverse events, and more secure in clinical applications, but the sample of this studywas fewer, further validation need to expand the sample size.