3.0Tesla MRI Multi-b-value Diffusion Weighted Imaging In The Diagnosis Of Female Pelvic Lesions

Objective:To explore the diagnostic value of Multi-b-value double exponential model for pelvic lesions using3.0Tesla MRI for the diagnosis of pelvic lesion.Materials and Methods:Fifty-six patients with six-nine pelvic lesions [35b enign case; Uterine leiomyoma12, Cysts12, Chocolate cyst6, Ovarian cystaden oma3, Teratoma2;34malignant cases:16cases of cervical cancer (squamous c ell carcinoma),15cases of endometrial carcinoma (adenocarcinoma),3cases of ovarian cancer] underwent MR750-diffusion weighted imaging scans,with b values of0,300,600,800,1200s/mm2, Functool-MADC software was used on AW451workstations for data processing, Regions of interest (ROI) which try to avoid the cystic degeneration, necrosis, bleeding,choose a larger the larger, uniform de nsity place, solid parts were measured on Cystadenomas, fat contents were meas ured on teratomas, The ROI as far as possible consistent with three measurement s (each no more than the floating range20mm2), Slow ADC valuen Fast ADC v alue, Standard ADC value, Fraction of fast ADC value were recorded and compa red between benign and malignant lesions. Finally, Standard ADC images were f used with axial T2fat-suppressed images, which can show the pelvic structure b etter and position the tumor accurately. The endometrial carcinoma and cervical cancer were compared to understand the diagnostic value of multi-b-value double exponential model for differentiating malignant tumor pathological types.Results:Slow ADC values [(1.74±0.89)×10-3mm2/s] and Standard ADC value s [(1.73±0.79)×10-3mm2/s] of benign lesions were larger than those of the malign ant lesions [Slow ADC values:(0.97±0.28)×10-3mm2/s; Standard ADC values:(1.11±0.27)×10-3mm2/s](P<0.01), and the difference of Slow ADC value was largest b etween benign and malignant lesions. Fast ADC values of both benign and malig nant lesions were significantly larger than the Slow ADC values[Benign:Slow A DC value=(1.74±0.89)×10-3mm2/s,Fast ADC value=(15.94±9.01)×10-3mm2/s; Malign ant:Slow ADC value=(0.97±0.28)×10-3mm2/s, Fast ADC value=(13.85±8.96)×10-3mm2/s], there were significant differences among Slow ADC values and Fast AD Cvalues between two groups (P<0.01). The each ADC value of both the endome trial carcinoma and cervical cancer have no differences(p>0.05),[The endometrial carcinoma:Slow ADC=(0.96±0.23)×10-3mm2/s, Fast ADC=(11.14±6.58)×10-3mm2/s, Thecervical cancer:Slow ADC=(0.91±0.29)×10-3mm2/s, Fast ADC=(17.24±10.49)×10-3mm2/s].Conclusion:DWI combining with the ADC value technology as a fast, accu rate, noninvasive imaging technique is very important for clinical diagnosis. As a functional imaging MRI-DWI which can monitor organization in the microstruct ure find tumor earlier than conventional morphological changes. In this paper, D WI double exponential decay model which can use a variety of parameters, desc ribing the features of pelvic tumors from several aspects and reflecting tumor tis sue changes at the molecular level can show lesions earlier than conventional M RI. Based on quantitative measurement to diagnosis tumor tissue, DWI can diagn ose primary malignant tumors which conventional MRI cannot diagnose. At the s ame time, it can provide the tumor blood perfusion, supposed to replace the enh ancement scanning, avoiding invasive examination and liver and kidney damage1ater. It can provide rich bases for the identification of benign and malignant pel vie tumors, But we found no statistical significance to identification the tumor p athological types. This is perhaps the small number of cases in this paper.