| Purpose:part1:To detect three-dimensional(3D) ultrasound appearance of fetal normal and abnormal supermaxilla bone’s anatomy using skeletal rendering mode, and to compare the success rate of3D images in different gestational age groups; part2:To investigate the errors and differences of various initial planes in the diagnosis of ceasmic teratism with three-dimensional ultrasonography; parti:To investigate the pattern of intrauterine growth in normal fetuses during15～21weeks and the correlation between gestational age and fetal bony intraorbital distance with Skeletal Rendering Mode of Three-dimensional Ultrasound.Method:part1:Using three-dimensional ultrasound skeletal rendering mode of voluson730and voluson E8ultrasound systems, the fetal supermaxilla bones were reconstructed, the supermaxilla bones include two hundred and sixty-one cases with the range from12to40gestaional weeks that were normal supermaxilla proved by2D ultrasound exam, three cases that were the specimens of fetal normal supermaxilla, and eight cases that were abnormal supermaxilla. The normal supermaxilla’s imaging success rates of different gestational ages were contrasted; part2:GE Voluson E8ultrasound machine was applied for the ultrasonic diagnosis. Three-dimensional reconstruction was performed to the round holes and slotted holes. Then the data was compared with the actual values. In this study, three-dimensional reconstruction was conducted to7cheiloschisis or cheilognathoschisis fetus and3samples. Then the width of the fracture was compared; part3:Using three-dimensional ultrasound skeletal rendering mode of voluson E8ultrasound systems, the87cases were reconstructed in nomal fetal facial skeletons, and were measured their bony intraorbital distance.Results:part1:Big anatomic structures of fetal supermaxilla in3D images can be shown, but detail can not. The success rate of normal fetal supermaxilla bone’s formation and structure with the3D image was97.9%during the gestation of12～15+6weeks,96.0%of16～21+6weeks,98.4%of22～27+6weeks,68.6%of28～35+6weeks,27.5%of36～40weeks. Through the X2test, there was no significant difference in the success rate of displaying among the gestation of12～15+6weeks,16～21+6weeks and22～27+6weeks. The success rate during the gestation of36～40weeks was the lowest among all the gestation. The success rate of cleft palate with3D image was100%(8cases). part2:The ratio of fracture width to real value ranged from0.90to1.10as the distance of probe and metallic strip ranged from30to90mm, and50to75mm, respectively. In the other conditions, the ratio was less than0.90. The extent of cheiloschisis or cheilognathoschisis width was dependent on the initial planes. Statistical difference was noted when the initial plane was vertical to the fracture. part3:The fatel bony intraorbital distance during15-21weeks was successfully detected in100%of the subjects. The linear relationship IOD=-4.65+0.9MA(the correlation coefficent was0.870)between the gestational age and the fetal bony intraorbital. Conclusion:part1:3D ultrasound can supply more detailed and comprehensive information of fetal supermaxilla bone. The better fit examine weeks for obtaining3D images are within12～35+6weeks, the best fit examine weeks are within16～27+6weeks. The function of3D skeletal rendering mode image can display cleft palate clearly.part2:The imaging obtained by ultrasonography was dissimilar to the real vision as the distance from the probe to the test item ranged from30to50mm and75to90mm, respectively. Under such conditions, it was hard to identify cheiloschisis or cheilognathoschisis. part3:The fetal bony intraorbital distance was accurately measured during15～21weeks, the relative coefficient between the gestational age and the fetal bony intraorbital are linearly related, and To provide a parameter for Down’s syndrome screening. |
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