The Research On The Effectiveness Of Wavefront-aberration Guided Combining Q-value Optimized LASEK On Refractive Error

Objective: To observe the pre and post operation visual acuity，characteristics ofcorneal topography,the parameters of wave-front aberrations, as well as thecomplications and their possible affecting factors.To further investigate new solutionof improving postoperative visual quality in an all around way for patients withrefractive errors.Methods: To have a retrospective analysis of pre-and post operative clinical dataof140cases (280eyes) that had gone through wavefront-guided combining Q-valueoptimized Laser subepithelial keretomileusis in their treatment of refraction error. Allpatients were required to take preoperative and postoperative examinations includingUCVA, BCVA, IOP measurements, refraction status, corneal thickness, cornealtopographic tests, namely corneal curvature nd posterior corneal surface height,WaveScan aberrometer test and so on. And fill in the NEI-RQL-42table.Anassessment of the treatment effectiveness of Wavefront-aberration guided combiningQ-value optimized LASEK was made in a relatively conclusive way.Results: There is no presence of severe postoperative complications. All but8patients （16eyes) have obtain vision acuity of1.0or more just1month afteroperation and later from then on. BCVA is improved for some patients. BCVAimprove one line in88eyes and2lines in46myopia eyes. About six months except6cases (12eyes) still have0.5level Haze, the remaining Haze were disappeared. Nomore than II Haze, BUT was reduction postoperative, but can be returned to thepreoperative level about six months. Postoperative corneal curvature and cornealthickness decreased significantly; There is a little increase of posterior corneal surfaceheight. RMS3, RMS4, RMS5, RMS6have all increased, with RMScoma as well as RMSsphere making the greatest contribution to the rising HOA(P<0.05), but noobvious changes for trefoil. NEI-RQL-42postoperative scores were significantlyhigher than preoperative ones.Conclusions:1UCBA after Wavefront-aberration guided combining Q-value optimized LASEKis predicative within expected range of refraction.2BCVA is improved in parts of the patients.3Postoperative patients have corneal sensitivity of central and BUT down, alongwith the time development, corneal sensitivity of central and BUT can be recovered tothe preoperative level.4. There is only a little rising of corneal posterior surface height and presence ofcorneal ectasia, further improving the safety of the operation.5Postoperative high order aberrations have all increased obviously, with coma andsphere RMS(root mean square) taking the greatest share with statistical significance,without too much influence of the visual quality after operation.