Clinical Observation Of The Sevoflurane Combined With Sulfentanyl For Anesthesia Induction In Invisible Intratracheal Intubation Under Different Conditions

Objictive: To observe and evaluate the clinical effects of hemodynamics and thequality of postoperative recovery under sevoflurane combined with sulfentanyl foranesthesia induction in invisible intratracheal intubation.Methods:Methods a total of eighty ASA I-II operation inpatients at the age of18to60undergoing elective ENT operations during the period from May2013to October2013in Yan’an University Affiliated Hospital.The patients were randomly allocated tofour groups with20cases each,who received anesthesia induction in invisibleintratracheal intubation under different conditions.All patients entered the operation roomfor routine detection,intravenous injected dezocine0.1mg/kg,then inhaled8%sevoflurane to anesthesia induction,intravenous sufentanil0.4-0.5ug/kg after patientswith loss of eyelash reflex.Group Q1(n=20) were given lidocaine cricothyroid membranepuncture surface anesthesia after entered the operation room,which compared with GroupQ2(n=20) with no surface anesthesia.Group J1(n=20) of control group were given surfaceanesthesia such as Group Q1after entered the operation room,after intravenous sufentanilthen injected rocuronium bromide.Group J2(n=20) with no surface anesthesia were givenintravenous sufentanil then injected rocuronium bromide.All patients waiting formandibular relaxation after invisible intratracheal intubation.Record the data of MAP、HR、SpO2from induction of general anesthesia（T0）、 the loss of eyelash reflex（T1）、 before invisible intratracheal intubation（T2）、immediately after endotracheal intubation（T3）and1min（T4）、3min（T5）、5min（T6）after invisible intratracheal intubation;Besides record the time from beginning to inhaled sevoflurane to the loss of eyelashreflex（t1）、from the beginning of sevoflurane to invisible intratracheal intubation （t2）、the time of spontaneous breathing recovery when patients after operation（t3）、time ofextubation（t4）；Meanwhile observe and evaluate intubation condition and adversereactions of invisible intratracheal intubation and awakening situation of patients.Results:1.Mean arterial pressure at each point from T0to T6in the four groups were asfollows.Compared with T1,MAP decreased in each group at T2（p＜0.05），MAP had nostatistically significant between the four groups at each time point（p＞0.05）.2.Heart rate at each point from T0to T6in the four groups were as follows.HR hadno statistically significant between the four groups at each time point（p＞0.05）.3.Record the date of four groups of t1-t4were as follows(Unit of t1、t2isseconds,Unit of t3、t4is minutes).Among the four groups, t1and t2had no statisticallysignificant （p＞0.05）.But for t3and t4,compared group Q1with group Q2and group J1with group J2had no statistically significant（p＞0.05）,while compared group Q1withgroup J1、group Q1with group J2、group Q2with group J1and group Q2with group J2hadstatistically significant（p＜0.05）.4.The Goldberg scores during intubation and the OAAS scores of the evaluation ofthe awakening were as follows. The Goldberg scores of four groups had no statisticallysignificant（p＞0.05）;For OAAS scores compared group Q1with group Q2and group J1with group J2had no statistically significant（p＞0.05）,while compared group Q1withgroup J1、group Q1with group J2、group Q2with group J1and group Q2with group J2had statistically significant（p＜0.05）.5.The number of adverse reaction cases of four groups during invisible intratrachealintubation had no statistically significant（p＞0.05）. Conclusion: Sevoflurane combined with sulfentanyl for anesthesia induction ininvisible intratracheal intubation can be safely used for induction of anesthesia to providea more stable hemodynamics.Meanwhile the quality of postoperative recovery hadsignificantly improved without the use of muscle relaxants.