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The Application Of3.0T MR Diffusion Weighted Imaging With Background Body Signal Suppression And Dynamic Enhancement In The Diagnosis And The Staging Of Gastric Carcinoma

Posted on:2015-08-12Degree:MasterType:Thesis
Country:ChinaCandidate:W W DengFull Text:PDF
GTID:2284330422481320Subject:Medical imaging and nuclear medicine
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Objective: To investigate the value of diffusion weighted imaging with backgroundbody signal suppression (DWIBS) combined with dynamic contrast enhancedmagnetic resonance imaging in the preoperative diagnosis and the TNM staging ofgastric carcinoma.Methods: Twenty-five patients which were confirmed gastric carcinoma in ourhospital by gastroscope biopsy from March2013to March2014were collected.Application of16channel dedicated coil, the equipment was Philips Achieva3.0TXsuperconducting MR scanner. The conventional MR、THRIVE and DWIBS sequence(b value select0and800s/mm2) were performed on all patients. In thepost-processing workstation, the original images were transmitted to observe thedepth of the cancer invasion, regional lymph node metastasis and distantmetastasis, and then to measure the thickness of the lesions and ADC values. Morethan two senior title of professional doctor by the double-blind method read allimages, and then the results were compared with the pathology findings, which theevaluation index of consistency used the kappa value.Results: All of the twenty-five patients had been completed MRI scan. Expect for onewas not obvious, twenty-four patients were revealed significantly strengthened inTHRIVE (twenty cases of non-uniform strengthen, and four cases of hierarchicalreinforcement). For the twenty patients with gastric carcinoma surgery, the accuracyof T-staging and N-staging respectively was80.0%(16/20) and75.0%(15/20), andcompared with surgical pathology, the consistency check is satisfied about thediagnosis of magnetic resonance imaging for gastric carcinoma staging. The ADCvalue of gastric carcinoma was lower than that of the distal stomach (P<0.001), andthe difference of ADC value between metastatic and non-metastatic lymph nodes wasstatistically significant (P<0.001).Conclusions: It is possible to show the location, infiltrating depth and the surroundingstructure transfer situation for DWIBS combined with THRIVE, and which is of greatimportance in the diagnosis and preoperative staging of gastric carcinoma; DWIBScan not only estimated from image signal of different metastatic lymph nodes, but if combined with measured ADC values and lymph node shorter diameter it canimprove the detection of metastatic lymph nodes.
Keywords/Search Tags:Gastric carcinoma, Diffusion weighted imaging, Dynamicenhancement, TNM staging
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