Comparative Study Of The Clinical Safety And Efficacy Between TURP And PKEP For Benign Prostatic Hyperplasia

Objective:To compare the clinical efficacy and safety between transurethral plasmakinetic enucleation of the prostate(PKEP) and transurethral resection(TURP) on benign prostatic hyperplasia(BPH).Methods:To completely randomly collect 200 cases of patients with BPH:100 patients underwent transurethral prostatectomy with PKEP,and 100 patients underwent TURP.Determination of intraoperative rinses uptake, the bleeding; Compare two groups introprative bleeding, rinses uptake, prostate resecting weight,operation time, bladder irrigation time,catheterization time and postoperative hospitalization days, complications. Follow-up for 6 months,compared two groups maximum urinary flow rate(Qmax) , residual urine volume(PVR) , serum prostate-specifc antigen(PSA) level,international prostate symptom score(IPSS),quality of life score(QOL).Results: The operation success rates were 100%(200/200).Comparison between PKEP group and TURP group included th following:intraoperative rinses uptake(404.7±112.8) vs (463.5±130.2)ml,introprative bleeding (118.5±11.8)vs(151.3±17.3)ml,prostatic resecting weight (29.9±5.4) vs (29.6±6.0)g,operating time(62.8±15.8) vs (47.4±15.5)min,postoperative bladder irrigation(2.0±0.8)vs(2.5±0.5)d,catheterization time(4.0±0.8)vs(4.5±0.5)d,postoperative hospital stay(6.0±0.8)vs(6.5±0.5)d,postoperative Blood Sodium Concentration(138.5±1.3) vs (136.9±1.4)mmol/l,Blood Sodium Concentration slippage(1.5±0.3) vs (3.0±0.6)mmol/l.Significant differences were found between the 2 groups (p<0.05) except prostatic resecting weight.group.After 6 months,71 cases of PKEP patients and 73 patients of TURP group completed follow-up.One and six months postoperatively,IPSS,QoL and Qmax were significantly improved in both groups (p<0.01),with no significant difference between the 2 group (p>0.05).Six months postoperatively,PVR improvement and PSA reduction were no significant difference.There were 5 cases of temporary urinary incontinence in PKEP group and 3 cases of temporary urinary incontinence in TURP group.There were 1 cases of urethrostenosis,1 cases of TURS and 1 cases of blood transfusion(200ml) in the TURP group.There were 1 cases of vesical neck constriction in PKEP group and 1 cases of vesical neck constriction in TURP group.Conclusions:PKEP and TURP have similar efficacy in the treatment of BPH,but PKEP is superior to TURP in safety,blood loss,TURS incidence rate,hospitalization expenses, surgical indication and complication rate.