| Rabbit coccidiosis is one of the most serious parasitic disease to rabbit breeding, whichhappens all around the country with clinical infection rates up to100%, causes enormouseconomic loss. Until now,17species of coccidia have been found in rabbit, Eimeria stiedai,which is provided with very strong infection power and the most serious harm during youngrabbit below30days, fatality rate will reach to the top range from60%～70%, is the highestpathogenicity coccidia live on the rabbit liver bile duct epithelial cells. Usually, Adult rabbitresistants successfully due to higher immunity, but the growth and development is affectedbadly, or to be a long-term carrier and become the source of the spread. The present study wasundertaken to investigate the infection of rabbit coccidian among part of breeding farms inXianyang city, meanwhile, carry out a research on E. stiedai pathogenicity, comparing thetreatment effection of anti-coccidia drug on clinical, in order to provide relevant scientificbasis for rabbit coccidiosis prevention and treatment.The circumstance of coccidian infection and the kinds of the coccidia were investigatedon rabbit in Xianyang city, Shaanxi province. The results suggested that the rate of coccidianinfection of rabbit was100percent and they were mixed infection. The most infectiveintensity is1301OPG (The number of oocysts per gram of feces). nine species of Eimeriaewere detected in infected rabbits, which were E. media, E. coeeicda, E. perfoans, E. magna, E.stiedae, E. piriformis, E. irrestidua, E. flaveseens and E. intesstinalis. E. media, E. coeeicdaand E. Perfoans were the predominant species.To have a further study in the pathogenicity of E. Stiedae, through artificial infectionmassive sporuleted oocyts and then carefully observation and the analysis on the clinicalsymptom and the lesion of the young rabbit. First, we need to divide the young rabbit into4groups, one control group and3challenged group, each chanllenged grounp was infected thesporuleted oocyts of E. stiedae by2×10~5、1×105and0.5×10~5. The result shows that after beinfected8days, the OPG value are2.19×10~7,2×107and1×10~7, respectively, relative weightgain rate respedtively be38.9%,58.0%,73.3%. It shows that the pathogenicity of E. Stiedaeis extremely strong. Selected about20to50-day-old Rex Rabbits who were naturally infected with coccidian,and randomly divided them into four groups. Diclazuril group, grams of ball powder（Clopidol）group, Robenidine group, non-drug control group,5rabbits each group.Respectively mixed a certain percentage of the drug in the feed, and let the rabbit feed freelyto compare their treatment of rabbit coccidiosis effect. Through clinical observation,analyzing the change of number of oocysts per gram of faeces, recording weight gain,calculating feed conversion ratio, the results showed, Diclazuril effect was significantly betterthan the grams of ball powder（Clopidol）(P <0.05) and Robenidine (P <0.05) in theinhibition of production of rabbit coccidia oocysts, the protection of rabbits on weight gainand increase of the feed conversion ratio, Robenidine group and grams of ball powder（Clopidol）group were less effective in anticoccidial. There was no significant difference innon-drug control group (P>0.05). |
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