Design,Synthesis And Properties Of Some Novel Fluorescence Chemosensors Based On Quinoline

Fluorescent chemosensor is a molecular device that molecular recognition events can be effectively expressed by the fluorescence signal. It is widely used to detect cation, anion and neutral molecules through fluorescent recognition. Fluorescent chemosensor has a lot of advantages such as easy operation, high sensitivity, high selectivity and real-time in situ detection. It has become a kind of effective means to test various metal ions in environment and organism. In recent years, a lot of research is to design and improve the identifying unit, but the luminescent groups generally use conventional fluorophores. Quinoline as a fluorophore with excellent optical and electrical properties has been extensively researched.In this paper, four novel small molecule fluorescence chemosensors which can detect metal ion have been designed and synthesized through quinoline fluorophore with different identification units. And studied their recognition properties for different metal ions, and made some meaningful results. This paper is divided into six chapters, and the main contents are as follows;(1) We introduce the principle of the fluorescent chemosensors and its progress in the identification of metal ions. According to this, we present the design ideas.(2) After being modified the 8-hydroxy-2-methyl quinoline, quinoline-based fluorescent sensor L has been synthesized. The sensor L has a high selectivity and sensitivity for Al3+ in methanol solvents. The linear relationship between L and Al3-was favourable. The detection limit of Al3+ was calculated to be 1.2×10-7M. The binding ratio was 1:1.(3) Chemosensor 1 has been syhthesized by substituting the hydrogen hydroxy of sensor L with ethyl bromoacetate. The sensor 1 has a high selectivity and sensitivity for Fe3+ in methanol solvents. The linear relationship equation curve was y =64.23x-325.3, and the detection limit was calculated to be 4.8×10-8M-1.It is Show that sensor 1 can be qualitative and quantitative analysis of Fe3+.(4) Quinoline-based dual chromophore chemical sensor M has been syhthesized. The recognition performance of sensor M for sensing Al3+ and Cr3+ has been measured respectively through different spectra tests.(5) Fluorescent chemosensor N which showed fluorescence quenching for Fe3+ has been syhthesized, and its fluorescence properties for recognizing Fe3+ has been achieved by fluorescence spectroscopy.(6) Summary and outlook.