SPECT/CT Fusion Imaging In The Diagnosis Of Benign And Malignant Spinal Lesions To Identify Clinical Significance

Objective To evaluate the clinical significance of99mTc-MDP SPECT/CTimaging in the differential diagnosis of benign and malignant lesions in the spine.Methods In our research, there are102cases which evaluated respectively bythe whole body bone SPECT imaging and SPECT/CT imaging and eventuallyfound153spinal lesions. We have pathological findings, magnetic resonance,and six months or more radiographic follow-up results as the final diagnosticcriteria.Results There are153spinal lesions in a total number, and the No. of the finaldiagnosis of malignant lesions and benign lesions is113and40. The sensitivity,specificity, and accuracy of SPECT imaging in the diagnosis of spinal lesionswere:84.07%,60.00%,77.78%, the positive predictive value is85.59%, thenegative predictive value is57.14%; which the result in the SPECT/CTimaging were92.92%,87.50%,91.50%, the positive predictive value is95.45%, the negative predictive value is81.40%. The sensitivity, specificity andaccuracy of SPECT/CT fusion imaging is significantly higher than SPECTimaging in the diagnosis of spinal benign and malignant lesions (P <0.05). Conclusion99mTc-MDP SPECT/CT fusion imaging combines with theadvantages of high sensitivity of SPECT and high specificity of CT, which hasgreat clinical significance in the differential diagnosis of spinal benign andmalignant lesions.