Value Of Lung Water Relevant Index Assessing The Severity And Prognosis Of Patients With Sever Burns Concurrent Acute Respiratory Distress Syndrome

Objective To assess the severity categories definition and prognosticvalue of lung water relevant index in patients with severe burns concurrent acuterespiratory distress syndrome (ARDS).Method The study included31adult severely burned patients with ARDS,and record the general clinical data and primary complications. All patients aremonitored by pulse Indicator continuous cardiac output (PICCO) plus system,and acute physiology and chronic health evaluation (APACHE) II score wasrecorded in the initial. The oxygenation index, extravascular lung water index(EVLWI), and pulmonary vascular permeability index (PVPI) at0,24,72hourswere analysed. All patients were divided into death and survival groups by the28-day mortality to analyse the difference of these index between tow groups toinvestigate the prognostic value of these index.Results The28-day mortality was67.7%(21/31), the inhalation injureand sepsis were the major complications which make effect to the prognosis.The oxygenation index at72hour in the survival group was significantly higherthan that in death group (P<0.05); the PVPI at48,72hours in the survival group was significantly lower than that in death group (P<0.05); the EVLWI at24,48,72hours in the survival group was significantly lower than that in death group(P<0.05). The accurate judgment of oxygenation index, PVPI and EVLWI wereincrease gradually as time went on after placing cathete, and these indexs at72hour were valuable indicators to prognosis. The receiver operating characteristiccurve (ROC curve) used to evaluate the prognosis accuracy of these indicatorswere no difference (P>0.05).Conculsion The Picco system continuously monitored to detect the lungwater relevant index was significant to the severity assesment and prognosticvalue in severely burned patients with ARDS in clinic.