The Risk Factors Analysis Of Acute Renal Failure After Operation Of Hypertensive Cerebral Hemorrhage

Purposes:Acute renal failure（ARF） is one of the common complications of hypertensioncerebral hemorrhage surgery, getting more and more attention of the clinicians,but italso puts limits on the application for common medicine of neurosurgicalpostoperative like mannitol and antibiotic, thus influencing the prognosis of patientsseriously, postponing in-hospital time and increasing economic burden. Therefore, weshould explore the cerebral hemorrhage postoperative risk factors of AFR and providebasis for searching for effective prevention and treatment measures.Methods:After collecting230cases of postoperative patients who had done thehypertension cerebral hemorrhage surgery in neurosurgery of our hospital. Analyzingtheir risk through building a database of excel software and then using SAS.8.02statistical analysis software for variable assignment and statistical analysis. Whenusing single factor analysis, the measurement data was indicated by mean+/-standarddeviation(x±s). Counting data was tested by using X2. Multiple factors wereanalyzed by using Logistics regression analysis. If P<0.05for the difference, it hasstatistic significance.Results:According to the diagnostic standard of ARF, those230cases were examined byusing regression analysis. Among them, there were75cases got postoperative ARF.Singe analysis: the average age(57.75+10.26) of those who got ARF was higher thanthose(45.63+11.59) not; the average ICU hospitalization days(7.43+4.65) of ARFgroups was typically more than the days(3.11+4.12) of groups without suffering ARF;the longer the surgery time, the higher the incidence of postoperative ARF. When theoperation time is less than2hours, the incidence of ARF is16.67%; when operationtime is between2hours and4hours, the incidence of ARF is22.92%; when thesurgery time is from4hours to6hours, the incidence is36.08%; if the time is morethan6hours, the incidence of postoperative ARF is64.00%. If patients’GCS grade between3to8point,9to12point,13to15point, the incidence of postoperative ARFrespectively are48.52%,31.68%,16.39%. The total mannitol volume(5280.42g) ofpatients with postoperative ARF was higher than the volume(3523.76g) of those not;The longer the application time of antibiotics after operating, the higher the incidenceof post operative ARF. Incidence(43.69%) of postoperative blood transfusion inpatients with ARF was more than patients without blood transfusion(23.62%).The analysis results of Multi-factor unconditioned logistic regression showed thattotal mannitol volume, application time of antibiotics, postoperative GCS evaluationare independent risk factors of postoperative ARF of hypertension cerebralhemorrhage.Conclusion:The risk factors of postoperative ARF of hypertension cerebral hemorrhage are asfollows: patients’ age, operative time, ICU postoperative hospitalization days, totalmannitol volume after operating are independent danger factors of hypertensioncerebral hemorrhage postoperative ARF. Referring to the past report of the relationsbetween the postoperative condition of other disease and the ARF, it indicated thatcerebral hemorrhage is a special disease and needs particular treatment method duringtherapy time. Suffering ARF after cerebral hemorrhage is not the disease of urinarysystem which isolate from cerebral hemorrhage. ARF is a performance of cerebralhemorrhage disease.