Yunpi Zhixie Granule In The Treatment Of Infantile Diarrhea Secondary Lactose Intolerance

Objective:By observing the change of the main efficacy on infantile diarrhea curative effect before and after the treatment, objective evaluation the clinical efficacy and safety of infantile diarrhea secondary lactose intolerance treated with yun spleen anti-diarrhea granule.Method:Select60patients with Pediatric diarrhea secondary lactose intolerance were randomly divided into the therapeutic group (30cases) and the control group (30cases). The treated group:Take Chinese Medicine Application on Navel according to the clinical syndrome differentiation. The basic prescription contains Chinese atractylodes, Kudzu, stems and hawthorn. Spleen deficiency syndrome add Radix Aucklandiae and Amomum tsao-ko, damp-heat syndrome add Scutellaria and Humifuse Euphorbia; improper diet syndrome add medicated leaven, corium and stomach ium galli; wind-cold syndrome add Notopterygium, Eupatorium fortune and stings of Gleditsia sinensis Lam. The control group:Smectite Powder and Bifid obacterium Tetravaccine tablets. Both the two groups take5days as1treatment course and observe1treatment course. Observes the two groups around the treatment defection frequency, defecate character, daily weight of stool, abdominal distension, appetite and vomiting improvement situations.Results:In the clinical study, the gender, age, course, total symptom score and indexing comparison of symptoms of the patients in two groups had no significant differences(P>0.05). At the end of the observation, the numbers of the cases that were cured, significant effective, improved and ineffective in the treatment group were7(23.30%)、11(36.70%、10(33.30%)、2(6.70%).Those in the controlled group were3(10.00%)、3(10.00%、15(50.00%、9(30.00%). The markedly effective rate and the whole effective rate were60.00%and93.3%respectively in the treated group, and were obviously higher than that in the control group(20.00%and70.00%,P<0.01).The scores of principal symptoms, secondary symptoms and total scores were all obviously lowered in the two groups, particularly in the treated group. So the difference was statistically significant (P<0.01), The treatment group was better than the control group. Groups in reducing the number of defection frequency, daily weight of stool, abdominal distension and vomiting, the difference was statistically significant (P<0.05), The treatment group has obvious advantages compared to the controlled group. But in the stool texture, appetite comparison showed that treatment group had no significant difference with control group (P>0.05).During the treatment period the two groups had no adverse reaction.Conclusions:Acupoint sticking therapy has a good therapeutic effect with no adverse effect, safety and convenient manipulation. It is worthy of clinical application.