Application Of Moca To Detect The Influence Of Hypertention On Cognitive

Cognitive impairments occurs as a consequence of many different factorss, including high blood pressure. However, in contrast to the general role of hypertension leading to cardiac, cerebral, and kidney impairments, the importance of hypertension leading to cognitive changes has received little attention.Objectives The aim of this study was to investigate the effect of hypertension on cognitive functions of patients with or without hypertention. We hypothesized that high blood pressure plays an important role for the alteration of cognitive impairments.Methods All the patients were outpatients or hospitalized patients in the Department of Internal Medicine, People’s Hospital of Qihe County from June2010to September2012. A total of200patients including130cases of patients with hypertension and70cases of patients with normal blood pressure were investigated in this study. According to MoCA score, hypertensive patients were divided into MoCA scores normal group and reduced group. The patients were also divided into different groups based on the levels of blood pressure and their educational condition, and ages.. MoCA scale is used to investigate the cognitive function of the patients. SPSS18.0software was employed to locate the differences between groups.Results (1) hypertension group compared with the normal blood pressure group, the MoCA total score visuospatial and executive function, attention, language, delayed recall score significantly lower, the difference was statistically significant (P <0.05).(2) hypertension group based on age and mean arterial pressure groups, using the chi-square test and linear analysis, suggesting that age and mean arterial blood pressure and MoCA score was a negative linear relationship.(3) hypertension group score normal and reduce the packet, the score to reduce group score higher than average normal group diastolic blood pressure, elevated pulse pressure Mean difference was statistically significant. MoCA ratings count (4) hypertension group grouped according to years of education, years of education is greater than12years is less than12years who visuospatial and executive function, language, abstract ability to score lower and the difference was statistically significant, but no significant difference in the total score, prompted MoCA scale remain subject to years of education, but the impact is small.(5) The comparison of different age and mean arterial pressure MoCA score, suggesting that the negative correlation between age and mean arterial pressure MoCA score.Conclusion1. Hypertensive patients are significantly lower on the MoCA total score and visuospatial and executive function、attention、language、the delayed recall score, suggesting that it is clear that hypertension has damage on the cognitive function of patients.2. Age and mean arterial pressure MoCA score showed a negative linear correlation, suggesting that it is more helpful to reduce mean arterial pressure and systolic blood pressure than reducing diastolic blood pressure to reduce cognitive impairment in patients.