| Objectives:To evaluate current evidence about cardioprotection of ischemic postconditioning(IPC) in patients with ST-segment elevation myocardial infarction (STEMI) undergoingprimary percutaneous coronary intervention (PPCI).and Provide evidence for clinicalchoice.Methods:Access to PubMed Embase,MEDLINE, Cochrane databases, Wanfang, CNKI, CBM,from January2005to January2012for finding relevant studies abou ischaemicPost-conditioning, in patients with ST-segment elevation myocardial infarction receivingPPCI. A meta-analysis of eligible studies was assessed by Review Manager5.1.Results:Ten randomized controlled studies met inclusion criteria.IPC Compared to thecontrol, observed outcomes such as peak creatine kinase WMD:469.23.08Units，CI(-622.50，-315.96（)P＜0.05），peak creatine kinasemyo-cardial band:WMD:64.71IU，CI(-91.34，-38.07)（P＜0.05）,The Left Ventricular Ejection Fractions，LVEF after7days:；WMD：4.47%CI(1.27，7.67)，（P=0.006）and after3monthsWMD：5.85%CI(2.58，9.12)，Z=3.51，(P=0.0005)Conclusions:Although current evidence shows that IPC provides cardioprotection to patientsundergoing primary PCI, larger adequately powered studies should be undertaken toconfirm its benefit. |
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