Quantification Of Left And Right Ventircular Function In Patients With Dilated Cardiomyopathy Using Real-time Three-dimensional Echocardiography

Objective：To explore the value of real-time three-dimensional echocardiography （RT-3DE）in the evaluation of left and right ventricular systolic function in patients with dilatedcardiomyopathy（DCM） and analysis the correlation of left and right ventricularsystolic function.Methods：Thirty five patients with DCM and forty healthy individuals were enrolled,byusing the contrast detection of the two dimensional echocardiography （2DE）,tissuedoppler imaging（TDI）and RT-3DE with Philips IE33color doppler ultrasonicdiagnostic apparatus. with a plain face Simpson method measured2DE indicators:leftand right ventricular systolic function parameters, including end-diastolic volume（EDV）, end-systolic volume （ESV）, ejection fraction （EF）, Measured TDI mitralvalve and tricuspid valve indicators: the interval and lateral wall peak motionvelocities at systole phase（Vs） and then calculating the average of bothVs,usingQLAB8.0quantitative analysis software measured RT-3DE indicators:Left and right ventricular systolic function parameters, including ESV, EDV, EF,examined the possible correlation of left ventricular and right ventricular functions.Results：1. Left and right ventricular systolic function parameters comparison: The resultsof EDV and ESV were significantly higher in patient group with DCM than those inthe control group（P<0.01）. The result of EF and the Vs of mitral valve and tricuspidvalve was signicantly lower in patients with DCM than in the control group （P<0.01）,2. The result of RT-3DE compared with2DE in patients with DCM, left andright ventricular systolic function parameters LVEF, RVEF has a good correlationbetween RT-3DE and2DE（LVEF: r=0.66, P<0.01, RVEF: r=0.64. P<0.01）,but theresult of LVEDV, LVESV, RVEDV, RVESV measured by2DE were significantlylower than RT-3DE measured,the result of LVEF, RVEF measured by2DE weresignificantly higher than RT-3DE measured, and there was statistically significant difference between the two methods（P<0.01）.3.The correlation analysis results of left and right ventricular systolic functionparameters of RT-3DE and TDI in patients with DCM: left ventricular function EF,TDI mitral valve indicators the interval and lateral wall peak motion velocities atsystole phase（Vs）, the average of both Vs had a positive relation（r₁=0.59, r₂=0.73,r₃=0.73, P<0.01）, right ventricular function EF, TDI tricuspid valve indicators theinterval and lateral wall peak motion velocities at systole phase（Vs）, the average ofboth Vs had a positive relation（r₁=0.63, r₂=0.88, r₃=0.85, P<0.01）,4. The correlation analysis results of left ventricular and right ventricular systolicfunction in patients with DCM: the result of LVEFand RVEF measured by RT-3DEare positively corrected （r=0.59, P<0.01）.Conclusions：1. RT-3DE can accurately assess of ventricular systolic function in patients withDCM by measuring the left and right ventricular systolic function parameters.2. Left ventricular systolic function had a positive relation with right ventricularfunction in patients with DCM and indicate that not only appear left ventricularsystolic function obstacle, also appeared different degree of right ventricular systolicfunction obstacle.