| Objective: To observe the immunosuppressant CsA and Bushentianjing Recipe is thetreatment of chronic patients with aplastic anemia efficacy evaluation to assess theintervention of the infection occurred in the course of patients with aplastic Bushentianjingof Chronic statistical treatment process, the number of serious infections, assessment riskof infection. Before and after treatment of chronic aplastic anemia patients bloodleukocytes, neutrophils, platelets, hemoglobin, provide the basis for the clinical use ofdrugs.Methods:32patients with chronic aplastic anemia patients were randomly dividedinto experimental and control groups, two groups of16cases, the test group with theimmunosuppressant CsA+BushentianjingFang, the control group was treated withimmunosuppressants CSA.Course of the two groups are six months. Observe the TCMsymptoms and clinical symptoms, statistics, the number of serious infections andmonitoring of white blood cells, neutrophils, platelets, hemoglobin.Results: The two groups of patients with initial Chinese medicine symptom score, qualityof life scores, blood on the findings, is not statistically significant and is comparable by ttest （P>0.05）.In TCM symptoms, the Chinese medicine symptom scores of test groupimproved, compared with the initial symptom score by paired t-test, there was nosignificant difference (P>0.05) when in one month，and there were significantly different(P <0.05) in three months and six months. The TCM symptoms score improvement of thecontrol group, the group with the initial symptom score compared by paired t-test was nosignificant difference (P>0.05). Times of serious infections of the test group and controlgroup after the t-test, P <0.05, was statistically significant. Quality of life scores after sixmonths of treatment, the two groups of patients quality of life scores have improved, the test group was more apparent, and quality of life scores in the two groups of patients sixmonths after the initial quality of life scores by paired t-test were significant differences (P<0.05), The quality of life scores between groups comparison by t-test, was significantdifference (P <0.05). In white blood cells, the three statistical two sets of data, month, threemonths, six months after the t test was no significant difference between the two groups,the experimental group group by paired t-test phase, initial white blood cell count than onemonth, three months and six months after the white blood cell count were significantlydifferent (P <0.05). Control group group compared by paired t-test, compared with theinitial white blood cell count, a month when no significant difference (P>0.05), threemonths and six months after the white blood cell count were significantly different (P<0.05). Course of treatment, the two groups of patients with hemoglobin bothimprovement between the two groups, one month, three months, six months after the threestatistical two sets of data was no significant difference (P>0.05) by t test. Comparisongroup, compared with the initial amount of hemoglobin, the two groups of patients onemonth, three months when the hemoglobin volume was no significant difference (P>0.05),a significant difference (P <0.05) in the six months after the hemoglobin. The course oftreatment, the patient’s neutrophils have improved between the two groups, no significantdifference (P>0.05) in the month, three months and six months after the two groups ofpatients with neutrophils. Comparison group, compared with the initial number ofneutrophils by paired t-test, the test group3had significant difference (P <0.05), while thecontrol group one month, three months, no significant difference (P>0.05), after sixmonths were significantly different (P <0.05). The course of treatment, the patient’s plateletcount improvement between the two groups a month, three months were not significantlydifferent (P>0.05), six months after the platelet count were significantly different (P<0.05), group comparison with the initial platelet number compared by paired t-test, thetest group of one month, three months and six months after the platelet count weresignificant differences (P <0.05), while the control group was no significant difference (P>0.05) a month, three months and platelet count were significantly different (P <0.05) aftersix months.Conclusion: compared with cyclosporine,treated with BushentianjingFang cansignificantly improve the patient’s TCM symptoms, reduce the risk of infection, andimprove quality of life. Two treatment regimens can significantly improve the number ofwhite blood cells, hemoglobin, the number of neutrophils, and there were no significant difference between them，but test group was more rapid. The two programs could increasethe number of platelets, Effect of BuShenTianJingFang with cyclosporine is morepronounced, and was more rapid. |
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