Clinical Study On Hyperandrongenism In Polycystic Ovary Syndrome Patients By Yin-Nourishing And Yang-Tonifying Staging And Kidney-Nourishing And Menstruation-Regulating With Compound Yasmin

Objective:To observe the efficiency of nourishing yin and tonifying yang staging and nourishing kidney and regulating menstruation and compound Yasmin on hyperandrongenism in PCOS patients.Method:This study includes two parts:theory study and clinical study.From refering to classic and modern articles,we can summary pathogenic mechanism and treatment method from Chinese Medicine and Modern Medicine angle of view.In clinical part,60patients who were in accordance with the inclusion criteria were divided into three groups randomly:group one(20cases) treated with TCM and Yasmin; group two(20cases) treated with TCM and Diane-35; group three(20cases) treated with TCM. Treatment period of three group are all six months. T、 LH、FSH、E2、SHBG、DHEAS levels were experimented before and after treatment. To compare the improving situation about menstruation,fatness,acne and hairness before treatment and after6months treatment.Results:The overall efficiency is88.89%in group one,83.33%in group two,68.75%in group three. The efficiency of ahead two groups is obviously above the Chinese Medicine group (p<0.05). Reproduction endocrine hormone levels modification efficiency above in group two was prior to group one.Group one and group two can regain the normal menstruation cycles, improve kidney-deficiency clinical symptoms. Improving efficiency about fatness,acne and hairness is prior to group three. Fatness modification efficiency in group one is prior to group two(p<0.05),otherwise acne modification efficiency in group two is prior to group one (p<0.05).Conclution:The efficiency of nourishing yin and tonifying yang staging and nourishing kidney and regulating menstruation and compound Yasmin on hyperandrongenism in PCOS patients is significant.It can modify the menstruation cycles, improve both fatness and hairness, reduce the volume of ovary and the number of antral follicles, degrade the the levels of T、LH、 DHEAS,upgrade the the level of SHBG.Especially the efficiency of improving fatness and water-sodium retention is significant, side effect of it is far lower than group two’s. The efficiency of improving acne and reproduction endocrine hormone is a little lower than group two’s.So it can be a best solution.