Incidence and disable rate of autoimmune disease have risen steadily inrecent years, which poses a therapeutic challenge to public health. Thepathogenesis of autoimmune disease has not yet been completely clarified,further restrict the progress of its therapies. Interleukin10is a kind of idealcytokine. Many studies have revealed the tight relationship between IL-10and the pathogenesis, progress, clinical manifestation of autoimmunedisease. With the development of molecular biology, some researchers havereported the association between IL-10gene polymorphism and geneticsusceptibility to autoimmune disease. On the basis of recently publishedarticles, this review will summarize the relationships between the two. |