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The Correlation Studies Of IL-10Gene Polymorphism And Genetic Susceptibility To Autoimmune Disease

Posted on:2014-02-24Degree:MasterType:Thesis
Country:ChinaCandidate:Q ZhanFull Text:PDF
GTID:2254330425454600Subject:Clinical Medicine
Abstract/Summary:PDF Full Text Request
Incidence and disable rate of autoimmune disease have risen steadily inrecent years, which poses a therapeutic challenge to public health. Thepathogenesis of autoimmune disease has not yet been completely clarified,further restrict the progress of its therapies. Interleukin10is a kind of idealcytokine. Many studies have revealed the tight relationship between IL-10and the pathogenesis, progress, clinical manifestation of autoimmunedisease. With the development of molecular biology, some researchers havereported the association between IL-10gene polymorphism and geneticsusceptibility to autoimmune disease. On the basis of recently publishedarticles, this review will summarize the relationships between the two.
Keywords/Search Tags:IL-10, gene polymorphism, autoimmune disease, systemic lupus erythematosus, rheumatoid arthritis
PDF Full Text Request
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