No-reflow: Mechanism, Diagnosis And Treatment For Patients With STEMI

No-reflow phenomenon in patients with ST-elevated myocardial infarction isassociated with high mortality and morbidity. Indeed it has been noted theincidence of this phenomenon varies from5%to50%in the set up of primarypercutaneous coronary interventions and the outcome in the long run is poor.Multiple mechanism have been put forward to explain this phenomenon butwithout really revealing its secret. Several diagnostic methods such asangiography, myocardial contrast echography, intravascular ultrasound amongothers, have helped study the changes that occurrence of no-reflow during primarypercutaneous coronary interventions. The treatment are also limited to reperfusionand prevention of embolisation while it is associated with a high long termmortality rate and other cardiac conditions such as malignant arrhythmias, cardiacfailure and sudden death. As such this review will attempt to look into the currentmechanism, diagnostic methods and available modes treatments which includemedical and preventive.