The Impact Of Cigarette Smoking And Sleeping Conditions On The Nonalcoholic Fatty Liver Disease Of Retiree Workers

Objectives(1) Awareness the prevalence of nonalcoholic fatty liver disease of retireeworkers.(2)To understand the impact of cigarette smoking and sleeping conditions onthe nonalcoholic fatty liver disease.MethodsA total of9829individuals (2,652men,7,177women) aged50to104yearsparticipated in a cross-sectional study based on Dongfeng-Tongji Cohort in Shiyan,China. Cigarette smoking and sleeping conditions were assessed with semi-structuredquestionnaires during face-to-face interviews. The questionnaire contents includegeneral condition, health-related behaviors, health checkup, blood biochemicalexamination. Chi-square measures or Fisher，s accurate algorithms were used tocompare the categorical data. Logistic analysis was used to examine the risks factorsinfluencing nonalcoholic fatty liver disease.Results(1)There were3752subjects who were diagnosed with NAFLD among the total9829individuals with the prevalence of38.2%,30.9%and40.9%respectively formale and female.(2)The prevalence of overweight or obesity and hypertensionbetween the smoking group and then control group were significantly different; theaminotransferase levels between the passive smoking group and control group weresignificantly different; the BMI and ALT levels were significantly different between the groups divided by sleep quality; the TG, FBG and HDL levels were significantlydifferent between the groups divided by sleeping duration; the ALT and bloodpressure levels were significantly different between the groups divided by sleepingtime; the BMI and FBG level were significantly different between the groups dividedby the duration of lunch break.(3) The sleeping time and lunch break were riskfactors for NAFLD adjusted for sex and age; sleeping duration and sleeping time wereindependent risk factors for NAFLD by stepwise logistic regression analysis.ConclusionsThe prevalence of NAFLD in retiree workers was higher compared with thegeneral population. Smoking is associated with BMI and blood pressure. Passivesmoking is associated with ALT level. Sleeping quality could influence the BMI andHDL-C. Sleeping duration is related to FBG, TG and HDL-C, and may be anindependent risk factor for NAFLD. Sleeping time is associated with ALT and bloodpressure, and may be an independent risk factor for NAFLD. Lunch break is related toBMI and FBG, and is a risk factor for NAFLD, but not independent.