Study Of Energy Acquisition Method For All-Digital PET

Positron emission tomography (PET) is a non-invasive functional imaging technology.By detecting the distribution of radioactive tracer uptake in vivo, PET is able to evaluate themetabolic activity, the biochemical reaction, the biological active and the perfusion of atissue dynamically and quantitatively. As a highly-sophisticated technology used in currentnuclear diagnostic and research, PET plays a significant role in the clinical diagnosis ofoncology, cardiovascular and nervous system, and also in the researches of pathology,pharmacology and medicine development of related conditions. Compared with theconventional PET system, digital PET data acquisition system (DAQ) can effectively solvethe issues arise form environment interference and calibration difficult. Therefore, digitalDAQ become a reach hotpot due to the wide use of digital signal processing technology.In this work, we have a research of a new digital pulse acquisition method-multi-voltage threshold sampling method (MVT). We research the key factors of energyacquisition, including noise, baseline, TDC accuracy, and threshold setting. We proposed anoise processing method based on MVT, to obtain accurate pulse energy information. Andwe also do the simulation of the impact of the accuracy of time-to-digital converter andthe number of actual hardware threshold for the MVT energy obtained. At last weproposed a baseline correction algorithm based on MVT.Also, we implement energy information acquisition module in the DAQ system basedon MVT method which is all digital and easy to calibration. We use this system getting theresult of the algorithms above, and laying the foundation for a all digital energyinformation acquisition of the PET system.At last, combining with the practical application, we make full use of the pulsecharacterization and digital signal processing algorithm, and implement energyinformation acquisition module in the DAQ system, which is developed at HuazhongUniversity of Science and Technology. We obtain an excellent energy performance thatcan fulfill the expected requirement.