A Study Of The Relation About Obstructive Sleep Apnea Hypopnea Syndrome And P Wave Dispersion

Objective:To discuss the relationship between the P wave dispersion and the severityof OSAHS,and to analysis the possible mechanism of how OSAHS leads to P wavedispersion change.Methods:Apnea hypopnea index (AHI),the lowest oxygen saturation(LSaO2) and the average oxygen saturation (MSaO2) level was measured bypolysomnography in patients with different severity OSAHS and control subjets.P wavedispersion (PWD) was calculated on the12-lead ECG. PWD was be compared withbetween the different groups. Results: PWD was significantly higher in the OSAHS groupwhen compared with the controls(46.09±13.40ms vs34.10±10.75ms, P<0.0001). Thethree groups of different degree of OSAHS was compared with each other, we foundapnea hypopnea index had a positive correlation with PWD(r=0.365, P=0.003). In addition,PWD was negatively correlated with the magnitude of the lowest oxygen saturationpercentage (r=-0.498, P<0.0001). Conclusion: This study shows that, P wave dispersionwas positively associated with the severity of OSASH. Atrial dilatation, hypoxemia maylead to the elevation of PWD, through the changes of structural and electrical atrial. Wecan use PWD for screening and evaluation of OSASH, predicts the occurrence of futurerisk of atrial fibrillation.