MRA Study Of The Morphology Of Willis’ Circle In Patients With Posterior Circulation Cerebral Infarction

Objective: To observe the morphology and patterns of willis’ circle in patients withposterior circulation cerebral infarction by using MRA sequence. Methods: Among1,224hospitalized patients with ischemic stroke in department of Neurology, XinjiangAutonomous Region People’ Hospital from January2010to April2012,173PCCI caseswere selected, To analyzes the structure characteristic of willis’ circle in PCCI patients.Comparison and analysis for the morphology of willis’ circle were made with167hospitalized patients with headache during the same period of time.173patients who werecomfier with the lesion by MRI were analyzed retrospectively with the clinical andimaging diagnosis characteristics. Results:(1)Top three clinical signs were: musclestrength decreased in108patients(62.4%), dizziness∕vertigo in85cases(49.1%), slurredspeech in74cases(42.8%); Middle infarction is the most common(56.1%) in PCCIpatients. The Most commonly infarcted area is pontine infarction(44.5%), followed by thethalamus(23.7%); PCCI mainly to single lesions infarction(68.8%), The Most commonlyinfarcted area is pontine infarction(31.2%), followed by the thalamus(15.6%); In themulti-focuses of infarction, the most common is brainstem and cerebral hemisphere(7.5%),followed by is brainstem and cerebellar infarction(6.9%).(2)The prevalence of thestructure anomaly is higher for Willis circle of PCCI(P﹤0.05). A1absence or hypoplasiais higher in PCCI patients(P﹤0.05), Left side is more higher(P﹤0.05);PCOA absenceis higher in PCCI(P﹤0.01), To compared with control group, The left and right side ofincidence are increased(P﹤0.05); PCCI often is accompanied by one side A1superiority(P﹤0.05), the left not statistically significant, the right incidence is higher thanthe control group(P﹤0.05). FTP is higher in PCCI(P﹤0.05), the right FTP notstatistically significant, the left incidence is higher than the control group(P﹤0.05).(3)The most common type of variation is PCOA absence(96%).To compare with the controlgroup, there is no statistically significant in unilateral and bilateral of PCOA absence andP1absence or hypoplasia. Double sided FTP no statistical significance, one side FTP iscommonly occur in PCCI(P﹤0.05). Conclusions：(1)The most common clinical signs is muscle strength, Middle infarction is the most common in PCCI patients, The Mostcommonly infarcted area is pontine infarction, In the multi-focuses of infarction, the mostcommon is brainstem and cerebral hemisphere;(2) The PCCI patient often isaccompanied by A1absence or hypoplasia、PCOA absence、FTP and one-side A1superiority.(3) Unilateral FTP is higher in PCCI patients.