The Analysis Of HPV Test In Follow-up Of170Cases Of Han And Uygur Patients With Cervical Cancer

Objective: To understand the treatment of patients with cervical cancer before and aftertreatment the human papilloma virus (HPV) change detection value.To approach theclinical significance of the high-risk human papillomavirus (HR-HPV) in the follow-up ofcervical carcinoma after operation. Methods: Data from a total of170cervical cancerpatients in Han and Uygur treated at The Xinjiang Uygur Autonomous Region people’sHospital from September2010to September2012were selected and reviewed，HPVmasculine，and the final diagnosis of histopathology for cervical cancer，of which115cases of patients with Uygur, Han patients55cases.The age22-56years old, average ageis43.3years old, with before treatment (HC-II) method for HPV-DNA detection,HPVwere detected after surgery or after chemotherapy respectively3,6,9,12,24months,170patients were followed up for2years. Compare the changes before and after treatmentHPV value, analysis with the extension of treatment time and HPV value trends. Results:1. There were significant differences age, parity and clinical stage of cervical carcinoma inUygur and Han nationality patients (P<0.05).2.170cases cervical cancer patients in Hanand Uygur received different treatment. Uygur patients received radiotherapy afteroperation were10cases (8.69%), radiotherapy plus chemotherapy were52(45.22%),cervical cancer radical surgery were21cases (18.26%), and postoperative chemotherapywere3cases (2.61%). Han patients received chemotherapy after operation were4cases(7.27%), cervical cancer radical surgery were17cases (30.91%), radiotherapy pluschemotherapy were19cases (34.55%), and chemotherapy radiotherapy aftersurgery were9cases (16.36%).3. With standard treatment, after3months,6months,9months,12months,24months of the negative cases were96，142，165，160，161,respectively. The end of the follow-up the HPV negative total number of cases in161cases (94.71%), the positive cases number of in9cases (5.29%). Conclusion: HR-HPVDNA detection plays an important role in cervical cancer follow-up. Effective treatmentcan effectively remove HPV, HPV detection and prognoses of cervical cancer are closelyrelated.