Dezocine Used For Elderly Patients With Postoperative Analgesic Efficacy And Safety Research

Objective:To object the different doses with dezocine used for elderly patients withpostoperation self-control analgesia effect and the influence of the circulation andrespiration system.Recording all kinds of side effects.Screening the best analgesiadoes,discusses its security.Methods: Patient who was accepted spinal surgery with generalanesthesia.80cases randomly,aged65-80years old,ASAⅠ-Ⅱ,sane,and can use patientself-controlled analgesia electronic pump.Divided them into four groups,each group has20cases in it.group A;group B;group C;group D.Record the circulation function,analgesiascores,calm score.Comfort score,adverse reactions and the frequency of press analgesiapump,in1h,4h,8h,24h,48.Results:1,There are no statistically significant in patients age,weight,sex,height,basic heart rate,basic systolic blood pressure,operation time.2,There areno statistically difference in heart rate,MAP,RR,SpO2of all time point.3,B group has thehighest VAS score,the lowest BCS score and the most times of press the analgesiapump,the difference has statistically significant.There are no statistical difference inanalgesia effect between group A,C,D.4,A group has the highest score of Ramsaygroup.The difference has statistically significant.There are no statistical difference inRamsay score between group B,C,D.5,The frequency of side effect was happen in A groupit has significant difference in C group,there are no statistical difference between group Band C.Conclusion:1.Dezocine can be safety and effectively used in elderly patients withpost operation PCIA.Analgesia effect exact.2.The best scheme is:Fentanyl10ug/kg+dezoc-ine200ug/kg+navoban5mg,additional does is1ml/time,lock time15min.