Radical Prostatectomy Of The Efficacy Of The Different Transperitoneal Approaches To Analyze And Compare

Objective To compare and study the treatment efficacy among laparoscopic radical prostatectomy (LRP) from opistho-pubis, LRP from abdominal cavity, open retropubic radical prostatectomy (RRP) as the treatment of localized prostate cancer. Methods48case of radical prostatectomy for prostate cancer patients in our hospital were retrospectively analyzed. The clinical date of13cases of patients undergoing LRP from opistho-pubis,11cases of patients undergoing RRP and24cases of patients undergoing LRP from abdominal cavity,which departed with14patients only undergoing LRP and10patients using endocrine before undergoing LRP, were analyzed retrospectively at our hospital. Indexes of before operation indexes, operating time, bleeding volume during operation, the duration of catheterization, relapse rate after operation were compared.Results patients of each group were all successful. The mean operationg time of RRP group was shorter than LRP group. There was statistical difference between the RRP group and LRP group (P<0.05). The mean bleeding volume during operation of RRP group and duration of catheterization and hospitalization stay after operation were more than LRP group (P<0.05). Hospitalization stay after operation and the time of bowel function recovery during LRP group from abdominal cavity were longer than LRP group from opistho-pubis (P<0.05), while duration of catheterization and removal time of drainage tube during LRP group from abdominal cavity were shorter than LRP group from opistho-pubis (P<0.05). There was no statistical difference between LRP with adjunctive therapy and LRP without adjunctive therapy. All patients were followed up for six months or thirty months,there was no statistical difference among three groups in the biochemical recurrence and continence rate (P>0.05).Conclusion LRP is not only featured with less blood loss and faster recovery, but also has the similar functional effect on tumor control and continence to RRP. The recovery time of LRP from abdominal cavity was longer but duration of catheterization was shorter than LRP from opistho-pubis. Whether or not adjunctive therapy was not accurate, and did not effect the tumor.