| The infectious disease caused by bacteria, viruses, mycoplasma, chlamydia and otherpathogenic microorganisms throughout the clinical departments, bacterial infection isthe most common among the total. So antibacterial drugs has become the most widelyused, most varieties, the largest amount of consumption of a class of drugs in clinicalmedicine, Including antibiotics, synthetic antibiotic, antifungal drugs and so on.Atpresent, problems of drug resistance to antimicrobial agents of infectious diseases havebecome increasingly prominent. Inappropriate antibiotic therapy,not only prolongedtreatment duration and hospital stay,mortality increased, costs increase to infectionpatient, also leads to the bacterial drug resistance. A last, Will be no cure situation.Theirrational use of antibiotics is mainly manifested in the following aspects: non-bacterialinfections medication, improper preventive medication or drug combination, improperchoice of drugs, exorbitance of starting point, improper drug dose, frequency, time,course of treatment, administration route, selected solvent and so on. Characteristics ofdrug use of antibacterial in China: two high and two low. That is: the high usage, thehigh starting point of usage; the low delivery rate, the low rationality.This study aimed to investigate the antibacterial drug characteristics and developmenttrend of the hospital, investigation and analysis of antibacterial use present situation andexisting problem, in order to promote the rational use of antibacterials and normativemanagement to provide reference., thus to achieve improve the use of antibacterialdrugs in the treatment of patients, improve their life quality and survival rate, reduce themortality rate, but also avoid unreasonably excessive use of antibiotics, delaying thedevelopment of drug-resistant bacteria and so on. 1. Analysis on use of antibacterials in clinic of a3A-Grade Hospital in2011-2012The Ministry of health regulations, outpatient antibiotic use rate can not exceed20%.The monthly monitoring of the use of antibacterial agents, the supervision of the use ofntibacterials in higher frequency, eliminate departments centralized drug phenomenon.And formulate concrete measures and penalties, in order to improve the rationality ofantibacterial use in hospital. By the analysis of use of antibacterials in clinic of thehospital in2011-2012, the outpatient usage of antibacterial drugs was20.17%in2012morebetter than26%in2011, explain that In the special rectification of antibacterials,combined with the hospital system of reward and punishment, through propaganda,training, investigation, evaluation, feedback and other means of application ofantibacterials for outpatient, can promote the reasonable use of antibacterials foroutpatient, further reduce the usage of antibacterials for outpatient. To continue tostrengthen the intervention measures, make the use of antibacterials for clinic morereasonable.2. Analysis the use of antibacterials on hospitalized patients of a3A-Grade Hospital in2011-2012According to the Ministry of health "guiding principles of clinical application ofantibacterials"(to abbreviate "guiding principles") and " national antibacterials clinicalapplication of special rectification program in2011", statistics and analysis the use ofantibacterials on hospitalized patients of a3A-Grade Hospital in2011-2012, from theresult we can discern that the usage rate and DDD of antibacterials improved in2012than2011, To further strengthen the management of antibacterials, precipitate thesituation of antibacterials use better. In order to improve the level of anti-infectivetherapy, operation department can be used as the next focus of remediation, continue to strengthen the supervision of preventive antibiotic application, in order to achieve thesafe, effective, economical use of antibacterials.3. Analyze the Application of prophylactic antibacterials in580patients undergoingtype I Incision operationThe hospital enforced combination interference on clinical application of antibacterialsundergoing type I Incision operation in2012October. The research contrast by therationality index change in before and after intervention of Application of prophylacticantibacterials in580patients undergoing type I Incision operation, estimate the effect ofinterventions, to provide the scientific basis for the rational use of antibacterial andmacro management. Through the comparison and analysis can be seen, Postinterventiongroup compared with the non-intervention group had obvious difference in applicationof prophylactic antibacterial undergoing type I Incision operation, The next step can toincrease the intervention measures, improved the level of perioperative antibacterialsreasonable application,... |