Analysis Of The Clinical Features Of Hospitalized Female Patients With ACS In10Years In A Grade Level Hospitals In Xinjiang

Purpose: Analysis the basic clinical information of hospitalized female patients with ACS. Explore thegeneral clinical features, risk factors, coronary lesion characteristics and short-term prognosischaracteristics of female ACS patients in our hospital.Methods: Retrospective analysis of hospital medical records of2021patients with ACS admitted in ourhospital in February2002-2012February,691cases of females (34.19%),1330cases of male(65.81%).Comparing female and male patients generally clinical data, the major risk factors, the results ofauxiliary examination, diagnosis, treatment, characteristics of coronary lesions and short-term prognosischaracteristics.Statistical analysis of the data..Results:①The basic clinical characteristics: female ACS patients have a higher average age than men(61.42±12.47，66.99±8.19，P<0.05);The low proportion of women than men showed symptoms of typicalchest pain (70.04%vs79.92%，P<0.05);Male smoking more significantly than women (67.89%vs6.07%,P <0.05); The differences of family history between men and women was no significant difference (P>0.05). Male have a higher proportion of the history of myocardial infarction than female (13.83%vs8.83%,P <0.05). Female with hypertension, diabetes, dyslipidemia, atrial fibrillation history ratios were higherthan male (73.52%vs52.18%，27.79%vs19.25%，15.92%vs11.43%，3.47%vs1.28%，P<0.05for all),female patients with hypertension grade Ⅲ ratio significantly more than males (47.76%vs26.69%，P<0.05); Female have a poor cardiac function (NYHA cardiac function grading≥2:49.06%vs40.83%,P <0.05), female heart function3,4significantly more than men (11.29%vs8.50%,6.80%vs3.08%, P<0.05).②The main auxiliary examination: the female in hospital basis heart rate higher than male（75.38±17.07vs72.51±14.85，P<0.05). Echocardiography showed female a higher LVEF value than male（60.27±9.92vs58.35±10.26，P<0.05), The ratio of wall motion abnormalities lower than men (46.71%vs52.79%，P<0.05); The cholesterol, low-density lipoprotein cholesterol and high-density lipoproteincholesterol levels of female admission were higher than men（4.60±1.20vs4.14±1.03，2.72±0.92vs2.50±0.80，1.28±0.41vs1.10±0.41，P<0.05）；.③The drug treatment of coronary heart disease: femalehave a lower usage of clopidogrel，heparin and statins than male （88.57%vs93.69%，48.48%vs64.89%，86.83%vs90.75%，p<0.05）;④Female ACS patients have a lower treatment of coronary angiography andrevascularization than male（27.79%vs49.85%，20.41%vs39.55%，P <0.05for all), and there is nosignificant difference in characteristics of coronary lesions（P>0.05）.⑤Both sexes was no difference inincidence of major complications in the hospital. The stroke incidence and mortality rates of majorcardiovascular events in hospital were higher in female (0.43%vs0.00%，4.63%vs2.63%，P<0.05).Conclusions: The age of female ACS patients were higher than male, their symptoms are often atypical,and female have a higher percentage of comorbidities,a lower usage of clopidogrel, heparin and statins, alower treatment of coronary angiography and revascularization than male. there is no significant differencein characteristics of coronary lesions. The stroke incidence and mortality rates in hospital of female patientswere higher than male.